Evidence map›Paper›PMID 33092054›Full record

ReviewMicromachines2020

The Future Application of Organ-on-a-Chip Technologies as Proving Grounds for MicroBioRobots.

Haley C Fuller, Ting-Yen Wei, Michael R Behrens, Warren C Ruder

Abstract readReview
In one paragraph

Review in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Skeletal Muscle Tissue Engineering: From Tissue Regeneration to Biorobotics.Cyborg and bionic systems (Washington, D.C.) · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haley C FullerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.ORCID 0000-0001-5020-9257
Ting-Yen WeiDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Michael R BehrensDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Warren C RuderDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.ORCID 0000-0003-0745-9933

Funding

Cardiovascular Bioengineering Training ProgramT32HL076124 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SANJEEV G SHROFF · 2005 to 2026
$7.0M
Cellular Approaches to Tissue Engineering/RegenerationT32EB001026 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN, ANDREW W, MONGA, SATDARSHAN SINGH · 2003 to 2024
$5.5M
Creating Magnetically Inducible Synthetic Gene Networks for Cell and Tissue TherapiesDP2GM132934 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RUDER, WARREN CHRISTOPHER · 2018 to 2018
$2.2M
mHealth-assisted conditional cash transfers to improve timeliness of vaccinationsR21TW010262 · FIC · DUKE UNIVERSITY · PI OSTERMANN, JAN, VASUDEVAN, LAVANYA · 2016 to 2017
$354k
Air Force Office of Scientific Research FA9550-18-1-0262National Science Foundation DMR 1709238NHLBI NIH HHS T32 HL076124NIBIB NIH HHS T32 EB001026NIGMS NIH HHS DP2 GM132934NIH HHS DP2-GM132934
6 · The paper itself

Abstract

An evolving understanding of disease pathogenesis has compelled the development of new drug delivery approaches. Recently, bioinspired microrobots have gained traction as drug delivery systems. By leveraging the microscale phenomena found in physiological systems, these microrobots can be designed with greater maneuverability, which enables more precise, controlled drug release. Their function could be further improved by testing their efficacy in physiologically relevant model systems as part of their development. In parallel with the emergence of microscale robots, organ-on-a-chip technologies have become important in drug discovery and physiological modeling. These systems reproduce organ-level functions in microfluidic devices, and can also incorporate specific biological, chemical, and physical aspects of a disease. This review highlights recent developments in both microrobotics and organ-on-a-chip technologies and envisions their combined use for developing future drug delivery systems.

Indexed as

drug deliverymicrobiorobotsmicrophysiological systemsmicroroboticsorgan-on-a-chip

Identifiers

PMID33092054
PMCPMC7589118

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.