ArticleClinical and experimental pediatrics2021
Celiac disease in children: Increasing prevalence and changing clinical presentations.
Article in Clinical and experimental pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Celiac Disease in Children with Idiopathic Nephrotic Syndrome-A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Celiac Disease on the Bed-Side: Embedding Case Finding and Screening in Hospitalized Children.Nutrients · 2023Article
- Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs.Dermatology and therapy · 2023Review
- Celiac disease in paediatric patients in the United Arab Emirates: a single-center descriptive study.Frontiers in pediatrics · 2023Article
- Clinical Presentation of Pediatric Celiac Disease Patients in the Qassim Region Over Recent Years.Cureus · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCeliac disease (CD) is a chronic autoimmune enteropathy. It results from genetic predisposition and exposure to gluten-containing food. The prevalence and presentation of CD vary among populations. PURPOSE: This study aimed to describe the prevalence and clinical characteristics of CD in children in Bahrain.
methodsWe retrospectively reviewed the medical records of children diagnosed with CD in the pediatric department, Salmaniya Medical Complex, Bahrain, in 1988-2018. Their clinical, biochemical, serological, and histopathological findings were documented. Adherence to the recommended gluten-free diet (GFD) was assessed.
resultsOf 86 patients with CD, 67 were included. The CD prevalence was 0.02%. A significant increase in prevalence in the last decade was observed (P<0.0001). Thirty-eight patients (56.7%) were males. The median (interquartile range) age at presentation was 4.45 (1.5-7.3) years. A family history of CD was positive in 13 out of 43 patients (30.2%). Pallor and failure to thrive were the most common presentations. The most frequent associated disease was iron-deficiency anemia in 23 patients (69.7%). Positive serology was found in 32 of 45 patients (71.1%). Marsh-Oberhuber type III was found in 16 of 35 patients (45.7%). Seropositive patients were significantly older (P=0.025) and had more severe duodenal histology (P=0.002). Adherence to GFD was poor in 27 patients (64.3%).
conclusionThis study revealed a significant increase in CD prevalence over the last decade. Atypical presentations were frequent. Most patients had poor adherence to GFD.
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