Evidence map›Paper›PMID 33091905›Full record

ReviewCardiorenal medicine2020

COVID-19-Associated Systemic Thromboembolism: A Case Report and Review of the Literature.

Pranav Mahajan, Bhagwan Dass, Nila Radhakrishnan, Peter A McCullough

Abstract readCase ReportsLetterReview
In one paragraph

Review in Cardiorenal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pranav MahajanMBBS, Department of Internal Medicine, Carle Foundation Hospital, Urbana, Illinois, USA, pranav71293@gmail.com.
Bhagwan DassDivisions of Hospital Medicine and Nephrology, University of Florida, Gainesville, Florida, USA.
Nila RadhakrishnanDivision of Hospital Medicine, University of Florida, Gainesville, Florida, USA.
Peter A McCulloughBaylor University Medical Center, Baylor Scott and White Heart and Vascular Institute, Texas A&M College of Medicine, Dallas, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCoronavirus disease 2019 (COVID-19) is a pandemic that has affected >188 countries, involved >24 million people, and caused >840,000 deaths. COVID-19, in its severe form, presents as acute respiratory distress syndrome (ARDS), shock, and multiorgan failure. Thrombotic microangiopathy of the lungs and kidneys has been observed in these patients. Elevated D-dimer levels have been observed in people with serious COVID-19 illness, and this could be helpful in guiding treatment with anticoagulation in these patients.

objectiveTo analyze the role of anticoagulation as a treatment modality for COVID-19.

methodsWe present the unique case of a COVID-19 patient who developed sepsis, ARDS, acute kidney injury, and deep-vein thrombosis (DVT), who was deteriorating clinically. She was treated with anticoagulation.

resultsThere was rapid recovery after treatment with systemic anticoagulation.

conclusionsSystemic anticoagulation could prove to be essential in the treatment of CO-VID-19. Further studies are required to assess its role in improving long-term morbidity and mortality in these patients.

Indexed as

Acute Kidney InjuryAnticoagulantsCOVID-19Cytokine Release SyndromeFemaleFibrin Fibrinogen Degradation ProductsHumansMiddle AgedRespiratory Distress SyndromeSARS-CoV-2SepsisThromboembolismThrombotic MicroangiopathiesTreatment OutcomeVenous ThrombosisAnticoagulantsFibrin Fibrinogen Degradation Productsfibrin fragment DAKIAnticoagulationARDSCOVID-19COVID-19-associated coagulopathyCytokine release syndromeD-dimerSARS-CoV-2ThromboembolismThrombotic microangiopathy

Identifiers

PMID33091905
PMCPMC7649692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.