ArticleEcotoxicology and environmental safety2021
Polyfluoroalkyl chemicals and the risk of kidney stones in US adults: A population-based study.
Article in Ecotoxicology and environmental safety, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 41 citations in OpenAlex.
- Risk predictive value of white blood cell count in patients with diabetes‑associated lower urinary tract symptoms: A population-based study.Clinics (Sao Paulo, Brazil) · 2026Article
- Inflammatory index-based nomogram for risk stratification of erectile dysfunction: a cross-sectional study with dual-cohort validation and mendelian randomization analysis.Translational andrology and urology · 2025Article
- Genetically predicted blood metabolites mediate the association between immune cell characteristics and urolithiasis: A Mendelian randomization study and mediation analysis.Genes & diseases · 2025Article
- Association between rheumatoid arthritis and kidney stones: A cross-sectional study of NHANES 2007-2020.Arthritis research & therapy · 2025Article
- Prevalence and Factors Associated with Kidney Stones in the Elderly Iranian Population: Findings from the Ardakan Cohort Study on Aging (ACSA).Archives of Iranian medicine · 2025Article
- Associations between the conicity index and kidney stone disease prevalence and mortality in American adults.Scientific reports · 2025Article
- Prevalence of kidney stones based on metabolic health and weight criteria: reports from the national health and nutrition examination survey 2007-2018 data analysis.Frontiers in physiology · 2025Article
- Association between exposure to per- and polyfluoroalkyl substances and kidney function: a population study.Frontiers in medicine · 2025Article
- Association between cardiometabolic index (CMI) and periodontitis in US adults: analysis of NHANES data (2009-2014).BMC oral health · 2024Article
- Association of chronic constipation and chronic diarrhea with renal stones: a cross-sectional study of the National Health and Nutrition Examination Survey 2007-2010.Translational andrology and urology · 2024Article
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and kidney stone: evidence from NHANES 2007-2018.BMC public health · 2024Article
- Arthritis increases the risk of erectile dysfunction: Results from the NHANES 2001-2004.Frontiers in endocrinology · 2024Article
- Association between ankle-brachial blood pressure index and erectile dysfunction in US adults: a large population-based cross-sectional study.Frontiers in endocrinology · 2024Article
- Serum glycolipids mediate the relationship of urinary bisphenols with NAFLD: analysis of a population-based, cross-sectional study.Environmental health : a global access science source · 2023Article
- Association between N, N-diethyl-m-toluamide exposure and the odds of kidney stones in US adults: a population-based study.Frontiers in public health · 2023Article
- Association between the systemic immune-inflammation index and kidney stone: A cross-sectional study of NHANES 2007-2018.Frontiers in immunology · 2023Article
- Relationship Between Blood Glucose Level and Prevalence and Frequency of Stress Urinary Incontinence in Women.Female pelvic medicine & reconstructive surgery · 2022Article
- Associations of exposure to polycyclic aromatic hydrocarbons and kidney stones in U.S. general population: results from the National Health and Nutrition Examination Survey 2007-2016.World journal of urology · 2022Article
- A higher TyG index is related with a higher prevalence of erectile dysfunction in males between the ages 20-70 in the United States, according to a cross-sectional research.Frontiers in endocrinology · 2022Article
- Dietary copper intake and the prevalence of kidney stones among adult in the United States: A propensity score matching study.Frontiers in public health · 2022Article
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10 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The potential nephrotoxicity of polyfluoroalkyl chemicals (PFCs) have received extensive attention. However, the relationship between PFCs and the risk of kidney stones remain unclear. This study aimed to examine the level of PFCs in the US population and its relationship with the risk of kidney stones. We investigated the serum levels of six PFCs in 8453 adult participants (≥20 years) from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2016, including perfluorodecanoic acid (PFDE), perfluorohexane sulfonic acid (PFHS), 2-(N-methyl-perfluorooctane sulfonamido) acetate (MPAH), perfluorononanoic acid (PFNA), perfluoroundecanoic acid (PFUA), and perfluorododecanoic acid (PFDO). Logistic regression model was used to evaluate the correlation between PFCs and kidney stones. Of the 8453 participants, 787 self-reported a history of kidney stones. After adjusting for gender, age, race, education, marital status, body mass index (BMI), hypertension, diabetes and estimated glomerular filtration rate (eGFR), we found that total PFCs and PFHS were positively correlated with the risk of kidney stones. Compared with the lowest tertile, the odds ratios with 95% confidence intervals (CI) with increasing tertiles were 1.30 (95% CI,1.08-1.59, p = 0.007) and 1.25 (95 CI%,1.00-1.52, p = 0.024) for total PFCs and 1.24 (95 CI%,1.03-1.51, p = 0.032), and 1.35 (95 CI,1.10-1.68, p = 0.005) for PFHS. Our study shows that total PFCs and PFHS were associated with an increased risk of kidney stones.
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