Evidence map›Paper›PMID 33091637›Full record

ArticleThe journal of allergy and clinical immunology. In practice2021

Asthma Prevalence and Mold Levels in US Northeastern Schools.

Evin J Howard, Stephen J Vesper, Barbara J Guthrie, Carter R Petty, Valeria A Ramdin, William J Sheehan, Jonathan M Gaffin, Perdita Permaul, Peggy S Lai, Lisa M Bartnikas and 5 more

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Indoor and Outdoor Fungal Allergens and Impacts on Respiratory Allergic Disease.The journal of allergy and clinical immunology. In practice · 2025
    Review
  2. Article
  3. Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.The Journal of allergy and clinical immunology · 2025
    Review
  4. The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025
    Review
  5. Review
  6. Article
  7. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
  8. The Environmental Microbiome, Allergic Disease, and Asthma.The journal of allergy and clinical immunology. In practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Evin J HowardBouvé College of Health Sciences, School of Nursing, Northeastern University, Boston, Mass.
Stephen J VesperUS Environmental Protection Agency, Center for Environmental Measurement and Modeling, Cincinnati, Ohio.
Barbara J GuthrieBouvé College of Health Sciences, School of Nursing, Northeastern University, Boston, Mass.
Carter R PettyInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Mass.
Valeria A RamdinBouvé College of Health Sciences, School of Nursing, Northeastern University, Boston, Mass.
William J SheehanDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Jonathan M GaffinHarvard Medical School, Boston, Mass; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Mass.
Perdita PermaulDivision of Pediatric Pulmonology, Allergy and Immunology, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY.
Peggy S LaiHarvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Mass.
Lisa M BartnikasDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Amparito CunninghamDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass.
Marissa HauptmanHarvard Medical School, Boston, Mass; Division of General Pediatrics, Boston Children's Hospital, Boston, Mass; Region 1 New England Pediatric Environmental Health Specialty Unit, Boston, Mass.
Diane R GoldHarvard Medical School, Boston, Mass; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Sachin N BaxiDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Wanda PhipatanakulDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: wanda.phipatanakul@childrens.harvard.edu.
Harvard University · USBoston Children's Hospital · USNortheastern University · USBrigham and Women's Hospital · USMassachusetts General Hospital · USNew York Hospital Queens · USOhio Environmental Protection Agency · US

Funding

SICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
ALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6M
The school microbiome and asthma morbidity in inner-city childrenR01AI144119 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAI, PEGGY SUE · 2019 to 2023
$3.7M
Indoor Air Quality and Respiratory Morbidity in School-Aged Children with Bronchopulmonary DysplasiaR01ES030100 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2019 to 2023
$3.7M
Environmental Risk Factors for Pediatric Sleep Disordered BreathingR01HL137192 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2017 to 2020
$3.5M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Atopy, Leptin and Potential Biomarkers of Comorbid Obesity and Asthma in Inner-City SchoolchildrenK23AI123517 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PERMAUL, PERDITA · 2017 to 2021
$1.1M
Evaluating the Impact of School Nut-Free PoliciesK23AI143962 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI BARTNIKAS, LISA MARIE · 2019 to 2023
$970k
Role of Peanut Allergen in Urban Schools and PreschoolsK23AI104780 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI SHEEHAN, WILLIAM JAMES · 2014 to 2018
$912k
ANALYZE AND EVALUATE POTENTIAL RISK FACTORS FOR AMYOTROPHIC LATERAL SCLEROSIS (ALS)R01TS000296 · TS · DARTMOUTH-HITCHCOCK CLINIC · PI STOMMEL, ELIJAH W · 2019 to 2019
$56k
ACL HHS R01TS000296ATSDR CDC HHS R01 TS000296NHLBI NIH HHS R01 HL137192NHLBI NIH HHS U10 HL098102NIAID NIH HHS K23 AI104780NIAID NIH HHS K23 AI123517NIAID NIH HHS K23 AI143962NIAID NIH HHS K24 AI106822NIAID NIH HHS R01 AI073964NIAID NIH HHS R01 AI144119NIAID NIH HHS U01 AI110397NIEHS NIH HHS R01 ES030100
6 · The paper itself

Abstract

backgroundAsthma is among the most common chronic diseases of children in the United States (US). Mold exposures have been linked to asthma development and exacerbation. In homes, mold exposures have been quantified using the Environmental Relative Moldiness Index (ERMI), and higher home ERMI values have been linked to occupant asthma.

objectiveIn this analysis of the School Inner-City Asthma Study (SICAS), we aimed to evaluate the ERMI's applicability to measuring mold in schools compared with homes and to examine the prevalence of asthma in relationship to students' demographics and the physical characteristics of school buildings.

methodsNortheastern US schools (n = 32) and homes (n = 33) were selected, and the 36 ERMI molds were quantified in a dust sample from each classroom (n = 114) or home. School building characteristics data were collected from SICAS. Asthma prevalence and student demographics data were obtained from government websites. Linear regression and mixed models were fit to assess the association of the current asthma prevalence and physical characteristics of the school, make-up of the student body, and the ERMI metric.

resultsLevels of outdoor group 2 molds were significantly (P < .01) greater in schools compared with homes. The presence of air-conditioning in school buildings correlated significantly (P = .02) with lower asthma prevalence.

conclusionThe prevalence of asthma in student bodies is associated with many factors in schools and homes.

Indexed as

Air Pollution, IndoorAsthmaChildFungiHousingHumansPrevalenceSchoolsUnited StatesAsthmaERMIHomesMoldNortheastSchools

Identifiers

PMID33091637
PMCPMC7946701
OpenAlexW3092693918

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.