ArticleJournal of sport and health science2021
The association of grip strength with cardiovascular diseases and all-cause mortality in people with hypertension: Findings from the Prospective Urban Rural Epidemiology China Study.
Article in Journal of sport and health science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Association between grip strength and hypertensive disorders of pregnancy: Prospective analyses in the Tongji-Huaxi-Shuangliu Birth Cohort.Chinese medical journal · 2026Article
- Heterogeneous grip strength trajectories and clinical determinants in middle-aged and older chinese patients with cardiovascular disease: a group-based trajectory modelling analysis of the CHARLS.BMC cardiovascular disorders · 2026Article
- Association of triglyceride-glucose related indices with cardiovascular diseases in individuals with low handgrip strength: a prospective cohort study of UK biobank.BMC cardiovascular disorders · 2026Article
- Preoperative exercise tolerance, nutritional-inflammatory markers, and outcomes after TEVAR for type B aortic pathology.Frontiers in cardiovascular medicine · 2026Article
- Trajectories of grip strength decline and risk of new-onset cardiovascular disease: evidence from the HRS and ELSA cohorts.Frontiers in public health · 2026Article
- One Enzyme, Many Faces: The Expanding Role of DPP3 in Cardiovascular and Critical Care.Journal of clinical medicine · 2025Review
- The simple task of lifting five kilograms serves as a predictor of age-related disorders in old adults.Scientific reports · 2025Article
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and hand grip strength in U.S. adults.Scientific reports · 2025Article
- Grip strength predicts postoperative ileus among patients undergoing abdominal minimally invasive surgery: a prospective multicenter cohort study.Surgical endoscopy · 2024Article
- Comparison of grip strength measurements for predicting all-cause mortality among adults aged 20+ years from the NHANES 2011-2014.Scientific reports · 2024Article
- [Grip strength and high blood pressure: a case-control study].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
- Combined association of aerobic and muscle strengthening activity with mortality in individuals with hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Multicenter randomized controlled trial of exercise in aortic dissection survivors: rationale, design, and initial hemodynamic data.Vessel plus · 2024Article
- Association between Handgrip Strength, Skinfold Thickness, and Trunk Strength among University Students.Diagnostics (Basel, Switzerland) · 2023Article
- Extracellular Vesicles and Hypertension.Advances in experimental medicine and biology · 2023Article
- Cost Effectiveness of the First-in-Class ARNI (Sacubitril/Valsartan) for the Treatment of Essential Hypertension in a Chinese Setting.PharmacoEconomics · 2022Article
- Association between Handgrip Strength and the Systemic Immune-Inflammation Index: A Nationwide Study, NHANES 2011-2014.International journal of environmental research and public health · 2022Article
- Muscular Strength in Risk Factors for Cardiovascular Disease and Mortality: A Narrative Review.Anatolian journal of cardiology · 2022Review
- Association of education levels with the risk of hypertension and hypertension control: a nationwide cohort study in Chinese adults.Journal of epidemiology and community health · 2022Article
- The comparative effects of exercise type on motor function of patients with Parkinson's disease: A three-arm randomized trial.Frontiers in human neuroscience · 2022Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundBoth hypertension and grip strength (GS) are predictors of mortality and cardiovascular disease (CVD), but whether these risk factors interact to affect CVD and all-cause mortality is unknown. This study sought to investigate the associations of GS with the risk of major CVD incidence, CVD mortality, and all-cause mortality in patients with hypertension.
methodsGS was measured using a Jamar dynamometer (Sammons Preston, Bolingbrook, IL, USA) in participants aged 35-70 years from 12 provinces included in the Prospective Urban Rural Epidemiology China Study. Cox frailty proportional hazards models were used to examine the associations of GS and hypertension and the outcomes of all-cause mortality and CVD incidence/mortality.
resultsAmong 39,862 participants included in this study, 15,964 reported having hypertension, and 9095 had high GS at baseline. After a median follow-up of 8.9 years (interquartile range, 6.7-9.9 years), 1822 participants developed major CVD, and 1250 deaths occurred (388 as a result of CVD). Compared with normotensive participants with high GS, hypertensive patients with high GS had a higher risk of major CVD incidence (hazard ratio (HR) = 2.39; 95% confidence interval (95%CI): 1.86-3.06; p < 0.001) or CVD mortality (HR = 3.11; 95%CI: 1.59-6.06; p < 0.001) but did not have a significantly increased risk of all-cause mortality (HR = 1.24; 95%CI: 0.92-1.68; p = 0.159). These risks were further increased if hypertensive participants whose GS level was low (major CVD incidence, HR = 3.31, 95%CI: 2.60-4.22, p < 0.001; CVD mortality, HR = 4.99, 95%CI: 2.64-9.43, p < 0.001; and all-cause mortality, HR = 1.93, 95%CI: 1.47-2.53, p < 0.001).
conclusionThe present study demonstrates that low GS is associated with the highest risk of major CVD incidence, CVD mortality, and all-cause mortality among hypertensive patients. High levels of GS appear to mitigate long-term mortality risk among hypertensive patients.
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