Evidence map›Paper›PMID 33091602›Full record

GuidelineHeart rhythm2021

2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.

Martin K Stiles, Arthur A M Wilde, Dominic J Abrams, Michael J Ackerman, Christine M Albert, Elijah R Behr, Sumeet S Chugh, Martina C Cornel, Karen Gardner, Jodie Ingles and 18 more

Open access · bronzeAbstract readPractice GuidelineConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Heart rhythm, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 5 pooled it
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 5 syntheses or guidelines pooled it, 292 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Guideline
  4. Guideline
  5. Pooled it
  6. Article
  7. Review
  8. The global landscape of SCD and approach to case work-up in Latin America: a LAHRS and SOBRAC survey.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Quantitative Histological Insights Into Sudden Arrhythmic Death Syndrome: Findings From a Forensic Autopsy Cohort.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 14 countries.

Martin K StilesWaikato Clinical School, Faculty of Medicine and Health Science, The University of Auckland, Hamilton, New Zealand.
Arthur A M WildeAmsterdam University Medical Center, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam, the Netherlands.
Dominic J AbramsBoston Children's Hospital, Boston, Massachusetts, USA.
Michael J AckermanMayo Clinic, Rochester, Minnesota, USA.
Christine M AlbertCedars-Sinai Medical Center, Los Angeles, California, USA.
Elijah R BehrCardiovascular Clinical Academic Group, Molecular and Clinical Sciences Institute, St George's, University of London, and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Sumeet S ChughCedars-Sinai Medical Center, Los Angeles, California, USA.
Martina C CornelAmsterdam University Medical Center, Vrije Universiteit Amsterdam, Clinical Genetics, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Karen GardnerUniversity of New South Wales, Canberra, Australia.
Jodie InglesAgnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, Australia.
Cynthia A JamesJohns Hopkins University, Baltimore, Maryland, USA.
Jyh-Ming Jimmy JuangCardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Stefan KääbDepartment of Medicine I, University Hospital, LMU Munich, Munich, Germany.
Elizabeth S KaufmanMetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA.
Andrew D KrahnThe University of British Columbia, Vancouver, British Columbia, Canada.
Steven A LubitzMassachusetts General Hospital, Boston, Massachusetts, USA.
Heather MacLeodData Coordinating Center for the Sudden Death in the Young Case Registry, Okemos, Michigan, USA.
Carlos A MorilloLibin Cardiovascular Institute, Calgary, Alberta, Canada.
Koonlawee NademaneeChulalongkorn University, Faculty of Medicine, and Pacific Rim Electrophysiology Research Institute at Bumrungrad Hospital, Bangkok, Thailand.
Vincent ProbstCHU de Nantes, Nantes, France.
Elizabeth V SaarelCleveland Clinic Lerner College of Cardiology at Case Western Reserve University, Cleveland, Ohio, and St Luke's Medical Center, Boise, Idaho, USA.
Luciana SacilottoHeart Institute, University of São Paulo Medical School, São Paulo, Brazil.
Christopher SemsarianAgnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, Australia.
Mary N SheppardCardiovascular Clinical Academic Group, Molecular and Clinical Sciences Institute, St George's, University of London, and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Wataru ShimizuDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Jonathan R SkinnerCardiac Inherited Disease Group, Starship Hospital, Auckland, New Zealand.
Jacob Tfelt-HansenDepartment of Forensic Medicine, Faculty of Medical Sciences, Rigshospitalet, Copenhagen, Denmark.
Dao Wu WangThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cedars-Sinai Medical Center · USCentenary Institute · AUSt George's, University of London · GBBoston Children's Hospital · USCentre Hospitalier Universitaire de Nantes · FRChulalongkorn University · THCleveland Clinic Lerner College of Medicine · USJiangsu Province Hospital · CNJohns Hopkins University · USLibin Cardiovascular Institute of Alberta · CALudwig-Maximilians-Universität München · DEMassachusetts General Hospital · USMayo Clinic · USMetroHealth Medical Center · USNational Taiwan University Hospital · TWNippon Medical School · JPRigshospitalet · DKStarship Children's Health · NZUniversidade de São Paulo · BRUniversity of Amsterdam · NL

Funding

Community-Based Evaluation of Sudden Cardiac Death in Hispanics/LatinosR01HL145675 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHUGH, SUMEET S. · 2019 to 2023
$2.4M
NHLBI NIH HHS R01 HL145675
6 · The paper itself

Abstract

This international multidisciplinary document intends to provide clinicians with evidence-based practical patient-centered recommendations for evaluating patients and decedents with (aborted) sudden cardiac arrest and their families. The document includes a framework for the investigation of the family allowing steps to be taken, should an inherited condition be found, to minimize further events in affected relatives. Integral to the process is counseling of the patients and families, not only because of the emotionally charged subject, but because finding (or not finding) the cause of the arrest may influence management of family members. The formation of multidisciplinary teams is essential to provide a complete service to the patients and their families, and the varied expertise of the writing committee was formulated to reflect this need. The document sections were divided up and drafted by the writing committee members according to their expertise. The recommendations represent the consensus opinion of the entire writing committee, graded by Class of Recommendation and Level of Evidence. The recommendations were opened for public comment and reviewed by the relevant scientific and clinical document committees of the Asia Pacific Heart Rhythm Society (APHRS) and the Heart Rhythm Society (HRS); the document underwent external review and endorsement by the partner and collaborating societies. While the recommendations are for optimal care, it is recognized that not all resources will be available to all clinicians. Nevertheless, this document articulates the evaluation that the clinician should aspire to provide for patients with sudden cardiac arrest, decedents with sudden unexplained death, and their families.

Indexed as

ConsensusFamilyArrhythmias, CardiacDeath, Sudden, CardiacGlobal HealthHumansMorbiditySurvival RateBrugada syndromeCardiac arrestCardiac geneticsCatecholaminergic polymorphic ventricular tachycardiaDefibrillatorExpert consensus statementGenetic counselingGuidelinesLong QT syndromePostmortemResuscitationSudden arrhythmic death syndromeSudden cardiac deathSudden unexplained deathVentricular arrhythmia

Identifiers

PMID33091602
PMCPMC8194370
OpenAlexW3092750687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.