Evidence map›Paper›PMID 33091423›Full record

ArticleThe Journal of investigative dermatology2021

Visualizing the Itch-Sensing Skin Arbors.

Yanyan Xing, Haley R Steele, Henry B Hilley, Yuyan Zhu, Katy Lawson, Taylor Niehoff, Liang Han

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. IL-31: State of the Art for an Inflammation-Oriented Interleukin.International journal of molecular sciences · 2022
    Pooled it
  2. MrgprC11 expression and function in vagal afferent nerves in the esophagus.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Article
  3. MrgprC11American journal of respiratory cell and molecular biology · 2025
    Article
  4. Regional Differences in Itch Transmission.The Journal of investigative dermatology · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Interleukin-31 and Pruritic Skin.Journal of clinical medicine · 2021
    Review
  9. MrgprC11Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanyan XingSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Haley R SteeleSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Henry B HilleySchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Yuyan ZhuSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Katy LawsonSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Taylor NiehoffSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Liang HanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA. Electronic address: liang.han@biology.gatech.edu.
Georgia Institute of Technology · US

Funding

The function of MrgprC11+ vagal sensory neurons in the airwayR01HL141269 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAN, LIANG · 2018 to 2022
$1.9M
Molecular and Cellular Mechanisms of Itch SensationR00NS087088 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAN, LIANG · 2016 to 2018
$739k
Molecular and Cellular Mechanisms of Itch SensationK99NS087088 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HAN, LIANG · 2014 to 2015
$190k
NHLBI NIH HHS R01 HL141269NINDS NIH HHS K99 NS087088NINDS NIH HHS R00 NS087088
6 · The paper itself

Abstract

Diverse sensory neurons exhibit distinct neuronal morphologies with a variety of axon terminal arborizations subserving their functions. Because of its clinical significance, the molecular and cellular mechanisms of itch are being intensely studied. However, a complete analysis of itch-sensing terminal arborization is missing. Using an MrgprC11

Indexed as

AnimalsMiceMice, Inbred C57BLNociceptorsPruritusReceptors, G-Protein-CoupledSensory Receptor CellsSkinMrgprx1 protein, mouseReceptors, G-Protein-Coupled

Identifiers

PMID33091423
PMCPMC8055730
OpenAlexW3094491005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.