ReviewNeuroscience and biobehavioral reviews2020
Neurotropism of SARS-CoV-2 and its neuropathological alterations: Similarities with other coronaviruses.
Review in Neuroscience and biobehavioral reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Audiovestibular Dysfunction Related to Long COVID-19 Syndrome: A Systematic Review of Characteristics, Pathophysiology, Diagnosis, and Management.International journal of molecular sciences · 2026Pooled it
- Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222).Frontiers in immunology · 2021Pooled it
- SARS-CoV-2 (COVID-19) and audio-vestibular disorders.International journal of immunopathology and pharmacologyPooled it
- Diffusion tensor imaging features of white matter pathways in the brain after COVID-19 infection.Radiologie (Heidelberg, Germany) · 2025Article
- Clinical and Functional Effects of Rehabilitation of Patients after COVID-19 Infection.Journal of clinical medicine · 2024Article
- Development of a Management App for Postviral Fibromyalgia-Like Symptoms: Patient Preference-Guided Approach.JMIR formative research · 2024Article
- Synergistic inhibition effects of andrographolide and baicalin on coronavirus mechanisms by downregulation of ACE2 protein level.Scientific reports · 2024Article
- Elevated Arterial Blood Pressure as a Delayed Complication Following COVID-19-A Narrative Review.International journal of molecular sciences · 2024Review
- SARS-CoV-2 infection and cognition in community-dwelling and nursing home residents in southern Switzerland.Brain, behavior, & immunity - health · 2024Article
- COGNITIVE, NEUROLOGICAL, NEUROPSYCHOLOGICAL AND NEUROPSYCHIATRIC ALTERATIONS IN POST-COVID-19 PATIENTS.Actas espanolas de psiquiatria · 2023Article
- Article
- Association between serologically confirmed COVID-19 infection and cognitive functioning in community dwelling older adults.Frontiers in neurology · 2023Article
- Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physical impairment.Neuroscience and biobehavioral reviews · 2022Review
- Review
- Article
- An mHealth App for Fibromyalgia-like Post-COVID-19 Syndrome: Protocol for the Analysis of User Experience and Clinical Data.JMIR research protocols · 2022Article
- Neurological consequences of COVID-19 and brain related pathogenic mechanisms: A new challenge for neuroscience.Brain, behavior, & immunity - health · 2022Review
- Neurologic complications of coronavirus and other respiratory viral infections.Handbook of clinical neurology · 2022Review
- Balance and visual reliance in post-COVID syndrome patients assessed with a robotic system: a multi-sensory integration deficit.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Reduction of Cardiac Autonomic Modulation and Increased Sympathetic Activity by Heart Rate Variability in Patients With Long COVID.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel coronavirus (SARS-CoV-2) emerged from Wuhan, China, and spread quickly around the world. In addition to fever, cough and shortness of breath, it was confirmed that the patients also have manifestations towards the central nervous system (CNS), especially those critically ill ones. In this review, we will discuss how SARS-CoV-2 gain access to the CNS and the possible consequences. Both SARS-CoV-2 and SARS-CoV-1 in 2002 share the same receptor angiotensin-converting enzyme 2 (ACE2), which can be found in the brain and mediate the disease process. Both direct attack of SARS-CoV-2 and the abnormal immune response in the CNS would contribute to the disease. Also, there is a relationship between SARS-CoV-2 and the occurrence of acute cerebrovascular diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.