Evidence map›Paper›PMID 33091364›Full record

ArticleLancet (London, England)2020

Use of adenovirus type-5 vectored vaccines: a cautionary tale.

Susan P Buchbinder, M Juliana McElrath, Carl Dieffenbach, Lawrence Corey

Abstract readLetterComment
In one paragraph

Article in Lancet (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Developing the next-generation of adenoviral vector vaccines.Human vaccines & immunotherapeutics · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Current clinical status of new COVID-19 vaccines and immunotherapy.Environmental science and pollution research international · 2022
    Review
  12. Adenovirus-based vaccines-a platform for pandemic preparedness against emerging viral pathogens.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  13. Article
  14. Article
  15. COVID-19 vaccination and HIV-1 acquisition.Lancet (London, England) · 2022
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Evolution of drug delivery systems: From 1950 to 2020 and beyond.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Susan P BuchbinderBridge HIV, San Francisco Department of Public Health, San Francisco, CA 94102, USA; Department of Medicine and Department of Epidemiology, University of California, San Francisco, CA, USA. Electronic address: susan.buchbinder@sfdph.org.
M Juliana McElrathFred Hutchinson Cancer Research Institute, Seattle, WA, USA; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, University of Washington, Seattle, WA, USA.
Carl DieffenbachDivision of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Lawrence CoreyFred Hutchinson Cancer Research Institute, Seattle, WA, USA; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, University of Washington, Seattle, WA, USA.

Funding

LOC: HIV Vaccine Trials NetworkUM1AI068614 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Dan H. Barouch, Lawrence Corey · 2011 to 2026
$1175.6M
LC: HIV Vaccine Trials NetworkUM1AI068618 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Margaret Juliana McElrath · 2011 to 2026
$483.6M
San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
Developing appropriate risk reduction interventions for pre-teensR21MH083308 · NIMH · WITS HEALTH CONSORTIUM (PTY), LTD · PI GRAY, GLENDA E, SIKKEMA, KATHLEEN J · 2008 to 2009
$331k
NIAID NIH HHS UM1 AI068614NIAID NIH HHS UM1 AI068618NIAID NIH HHS UM1 AI069496NIMH NIH HHS R21 MH083308
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenovirus VaccinesCoronavirus InfectionsPandemicsPneumonia, ViralViral VaccinesAdenoviridaeBetacoronavirusCOVID-19COVID-19 VaccinesGenetic VectorsHumansSARS-CoV-2Vaccines, SyntheticAdenovirus VaccinesCOVID-19 VaccinesVaccines, SyntheticViral Vaccines

Identifiers

PMID33091364
PMCPMC7571904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.