Observational studyThe clinical respiratory journal2021
Are frailty and patient-reported outcomes independent in subjects with asthma? A cross-sectional observational study.
Observational study in The clinical respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Exploring the association between asthma and frailty: a cross-sectional and a bidirectional Mendelian randomization study.Archives of medical science : AMS · 2026Article
- Relationship of the oxidative balance score with the risk of frailty and mortality in patients with asthma: a mediation analysis of NHANES.BMC pulmonary medicine · 2025Article
- Connecting the Dots Between Asthma Control and Frailty in Older Adults With Moderate to Severe Asthma.CHEST pulmonary · 2025Article
- Association between Frailty and Asthma.Medicina (Kaunas, Lithuania) · 2024Article
- Olfactory decline develops in parallel with frailty in older US adults with obstructive lung diseases.International forum of allergy & rhinology · 2024Article
- Frailty Prevalence and Association with Clinical Outcomes in Interstitial Lung Disease, Asthma, and Pleural Disease.Geriatrics (Basel, Switzerland) · 2023Review
- The causal relationship between risk of developing bronchial asthma and frailty: a bidirectional two-sample Mendelian randomization study.Frontiers in medicine · 2023Article
- Handgrip strength as a diagnostic tool for frailty risk in elderly patients with moderate to severe asthma.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Article
- Article
- Are frailty and patient-reported outcomes independent in subjects with asthma? A cross-sectional observational study.The clinical respiratory journal · 2021Observational
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
introductionThis study examined the possible associations between frailty and patient-reported outcomes (PROs) in elderly patients with asthma.
methodsParticipants completed the Kihon Checklist for frailty screening as well as the following tools for measuring generic- and disease-specific health-related quality of life (HRQOL) and asthma control; the Medical Outcomes Study 36-item short form (SF-36), the Hyland Scale (global scale), the Asthma Quality of Life Questionnaire (AQLQ), the Asthma Control Test (ACT), and the Asthma Control Questionnaire (ACQ).
resultsOf 69 consecutive outpatients with asthma, 38 (55.1%), 21 (30.4%), and 10 (14.5%) were classified as robust, pre-frail, and frail, respectively. Eight out of 52 patients with asthma in the elderly (AIE) (>65 years old) (15.4%) were considered as being frail. The Kihon Checklist total score was significantly correlated with all the scores obtained from the SF-36, Hyland Scale, AQLQ, ACT, and ACQ. All these scores were significantly different between groups with and without frailty. From the viewpoint of correlation coefficient, SF-36 Physical Functioning correlated most strongly with a coefficient of -0.68 (P < .01), and the Hyland Scale score was second (R DISCUSSION: There were significant associations between frailty and PROs, particularly generic perception of HRQOL. Since the Kihon Checklist and PROs such as the HRQOL overlap somewhat in their evaluation of the patients' condition, there might be some similarities in the conceptual frameworks of frailty and quality of life.
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