Evidence map›Paper›PMID 33090695›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2020

Using Medicare claims in identifying Alzheimer's disease and related dementias.

Siddharth Jain, Paul R Rosenbaum, Joseph G Reiter, Geoffrey Hoffman, Dylan S Small, Jinkyung Ha, Alexander S Hill, David A Wolk, Timothy Gaulton, Mark D Neuman and 3 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Unraveling disparities in county-level dementia diagnosis prevalence across the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Article
  7. Article
  8. Evaluating linked ICD-10 Medicare claims data as a method of dementia case ascertainment in research settings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. RaiLED-AD: Rationale-Guided Knowledge Transfer for Alzheimer's Disease Prediction from Electronic Health Records.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2025
    Article
  10. Observational
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Emerging approaches to multiple chronic condition assessment.Journal of the American Geriatrics Society · 2022
    Article
  17. Validation of Claims Algorithms to Identify Alzheimer's Disease and Related Dementias.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  18. Identification of Dementia in Recent Medicare Claims Data, Compared With Rigorous Clinical Assessments.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  19. Article
  20. Identifying Medicare beneficiaries with dementia.Journal of the American Geriatrics Society · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Siddharth JainCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Paul R RosenbaumThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph G ReiterCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Geoffrey HoffmanDepartment of Systems, Populations and Leadership, University of Michigan School of Nursing, Ann Arbor, Michigan, USA.
Dylan S SmallThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jinkyung HaDivision of Geriatric and Palliative Medicine, Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Alexander S HillCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
David A WolkDepartment of Neurology, The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Timothy GaultonThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mark D NeumanThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Roderic G EckenhoffCenter for Perioperative Outcomes Research and Transformation, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lee A FleisherThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jeffrey H SilberCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Funding

Neurocognitive Disorder after Appendectomy in the Elderly: A Natural ExperimentRF1AG055390 · NIA · CHILDREN'S HOSP OF PHILADELPHIA · PI SILBER, JEFFREY H · 2017 to 2017
$2.2M
NIA NIH HHS RF1 AG055390NIA NIH HHS RF1-AG-055390
6 · The paper itself

Abstract

introductionThis study develops a measure of Alzheimer's disease and related dementias (ADRD) using Medicare claims.

methodsValidation resembles the approach of the American Psychological Association, including (1) content validity, (2) construct validity, and (3) predictive validity.

resultsWe found that four items-a Medicare claim recording ADRD 1 year ago, 2 years ago, 3 years ago, and a total stay of 6 months in a nursing home-exhibit a pattern of association consistent with a single underlying ADRD construct, and presence of any two of these four items predict a direct measure of cognitive function and also future claims for ADRD. DISCUSSION: Our four items are internally consistent with the measurement of a single quantity. The presence of any two items do a better job than a single claim when predicting both a direct measure of cognitive function and future ADRD claims.

Indexed as

administrative dataAlzheimer's diseaseAlzheimer's disease and related dementiascognitive impairmentdementiahealth and retirement studyMedicareMedicare claims

Identifiers

PMID33090695
PMCPMC8296851

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.