ReviewOphthalmology and therapy2020
Dry Eye Disease: Early Recognition with Guidance on Management and Treatment for Primary Care Family Physicians.
Review in Ophthalmology and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06525961 (A Single-center, Open-label, Single-arm Study to Evaluate the Effectiveness and Safety of Extra Nasal Neurostimulator in Patients With Dry Eye Disease Dissatisfied With Artificial Tears), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-center, Open-label, Single-arm Study to Evaluate the Effectiveness and Safety of Extra Nasal Neurostimulator in Patients With Dry Eye Disease Dissatisfied With Artificial Tears
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Association between dry eye disease and depression: An umbrella review.Frontiers in public health · 2022Pooled it
- Effect of Bioptron light therapy on dryness of eyes in postmenopausal women: a randomized controlled trial.Lasers in medical science · 2026Trial
- Trial
- Electronics-Free Visual Monitoring of Dry Eye Disease-Related Tear Biomarkers Using Smart Scleral Lenses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Model of ocular surface ion and water transport predicts efficacy of dry eye therapeutics.The Journal of general physiology · 2026Article
- Prevalence and severity of dry eye disease among ophthalmologists, optometrists, and nurses: a cross-sectional questionnaire-based survey.International ophthalmology · 2026Article
- Benchmark evaluation of video large language models in quality assessment of science popularization videos for dry eye.Scientific reports · 2026Article
- Focus on sex hormone axis disorder: exploring the susceptibility mechanism of dry eye in perimenopausal women.Frontiers in medicine · 2026Review
- Dry Eye Disease: From Causes to Patient Care and Clinical Collaboration-A Narrative Review.Ophthalmology and therapy · 2025Review
- Overview of Dry Eye Disease for Primary Care Physicians.Medicina (Kaunas, Lithuania) · 2025Review
- Efficacy of povidone and propylene glycol-based artificial tears in the treatment of dry eye disease.Arquivos brasileiros de oftalmologia · 2025Article
- Dry eye disease treatment improves subjective quality-of-life responses in patients with AMD, independent of disease stage.PloS one · 2025Article
- Prevalence and determinants of work-related ocular symptoms among dentists of Bangladesh: A cross-sectional study.PloS one · 2025Article
- Prevalence of eye and adnexal disorders among elderly inmates in Taiwan prisons.BMC public health · 2024Article
- Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists.Annals of medicine · 2023Review
- Subjective dry eye symptoms and associated factors among the national general population in China during the COVID-19 pandemic: A network analysis.Journal of global health · 2023Article
- A Comprehensive Assessment of Tear-Film-Oriented Diagnosis (TFOD) in a Dacryoadenectomy Dry Eye Model.International journal of molecular sciences · 2023Article
- Comparison of the Ocular Surface Disease Index and the Symptom Assessment in Dry Eye Questionnaires for Dry Eye Symptom Assessment.Life (Basel, Switzerland) · 2023Article
- Recent Advances of Ocular Drug Delivery Systems: Prominence of Ocular Implants for Chronic Eye Diseases.Pharmaceutics · 2023Review
- Rheumatoid Arthritis Associated with Dry Eye Disease and Corneal Surface Damage: A Nationwide Matched Cohort Study.International journal of environmental research and public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary care presentations of dry eye disease (DED) are common and pose a diagnostic challenge due to the variety of symptoms and the absence of certainty for family practitioners. While there are many published articles on the topic, the 2017 Tear Film and Ocular Surface Society Dry Eye Workshop was a landmark report in distinguishing multifactorial differences. Redefined terms clarified the DED disorder. The ocular surface-the tear/air interface-is the primary refractive component of the eye, which is why DED is so significant and impacts vision. There is a high prevalence of DED in the community, ranging from 5% to 30% of people across multiple studies. Elderly patients have up to 75% increased risk of DED and receive more intensive treatment than younger age groups. DED is also more common in women than men, occurring in 9.8% of postmenopausal women. The causes of DED span defective lacrimal apparatus and systemic disorders. Despite its prevalence, up to one-half of patients with confirmed DED do not receive proper alleviating treatment. Risk factors on functional and environmental bases follow. Tools to elicit a diagnosis more confidently are outlined using the Ocular Surface Disease Index (OSDI) and the Symptom Assessment in Dry Eye questionnaires (SANDE). Lacritin, lutein, vitamin A, and balanced nutrition are essential contributors to maintaining healthy eyes with appropriate management and treatment. The authors hope that this paper will prompt a more accurate and expedient diagnosis of DED in primary care practice and an earlier recognition of specialist referrals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.