Evidence map›Paper›PMID 33089482›Full record

ArticleDigestive diseases and sciences2021

Prevalence and Associated Dietary Factors of Rome IV Functional Gastrointestinal Disorders in Rural Western Honduras.

Dalton A Norwood, Lucia B Dominguez, Andrea A Paredes, Eleazar E Montalvan, Aida Rodriguez Murillo, Michael K Dougherty, Olafur S Palsson, Ricardo L Dominguez, Douglas R Morgan

Erratum issuedAbstract read
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In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Dalton A NorwoodWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Lucia B DominguezWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Andrea A ParedesWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Eleazar E MontalvanWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Aida Rodriguez MurilloWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Michael K DoughertyDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, 4182, Bioinformatics, 130 Mason Farm RD, Chapel Hill, NC, 27599-6134, USA.
Olafur S PalssonDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, 4182, Bioinformatics, 130 Mason Farm RD, Chapel Hill, NC, 27599-6134, USA.
Ricardo L DominguezWestern Honduras Gastric Cancer Prevention Initiative, Western Regional Hospital, Hospital de Occidente, Avenida Solidaridad, 41101, Santa Rosa de Copan, Honduras.
Douglas R MorganDivision of Gastroenterology and Hepatology, The University of Alabama at Birmingham (UAB), 373 Boshell Building, 1720 2nd Avenue South, Birmingham, AL, 35294-0012, USA. drmorgan@uabmc.edu.ORCID http://orcid.org/0000-0002-1136-0963
Western Regional Hospital · NPUniversity of North Carolina at Chapel Hill · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe literature is limited regarding the prevalence of functional gastrointestinal disorders (FGIDs) in Central America, and the role of dietary factors.

methodsThe Rome IV diagnostic questionnaire and National Cancer Institute Diet History questionnaire were administered in one-on-one interviews to a distributed cross section of the general adult population of Western Honduras. Our aim was to estimate prevalence of common FGIDs and symptoms and their relationships to dietary habits.

resultsIn total, 815 subjects were interviewed, of whom 151 fulfilled criteria for an FGID (18.5%). Gastroduodenal FGIDs were noted in 9.4%, with epigastric pain syndrome (EPS) more common than postprandial distress syndrome, 8.5% versus 1.6%. Among bowel disorders, functional abdominal bloating (FAB) was most prevalent (6.3%), followed by irritable bowel syndrome (3.6%), functional diarrhea (FDr; 3.4%), and functional constipation (1.1%). A significant inverse association was noted between regular bean intake and any FGID (OR 0.41, 95% CI 0.27-0.63), driven by IBS and FDr. Vegetable consumption was associated with lower prevalence of functional diarrhea (OR 0.12; 95% CI 0.04-0.35) and any diarrheal disorder (OR 0.11; 95% CI 0.04-0.31). Subjects with a median daily intake of ≥ 4 corn tortillas had 1.75 (95% CI 1.22-2.50) times the odds of having any FGID.

conclusionsFGIDs were common in this rural low-resource setting in Central America, with an intriguing distribution of specific FGIDs. EPS and FAB were common, but IBS was not. Local dietary factors were associated with specific FGIDs, suggesting that diet may play a role in global variations of FGIDs.

Indexed as

Feeding BehaviorGastrointestinal DiseasesAdultCross-Sectional StudiesFemaleHondurasHumansMalePrevalenceRural HealthSurveys and QuestionnairesSymptom AssessmentDietDyspepsiaFODMAPsFunctional gastrointestinal disordersIrritable bowel syndromeRome IV criteria

Identifiers

PMID33089482
OpenAlexW3094304073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.