Evidence map›Paper›PMID 33089458›Full record

ReviewMedical & biological engineering & computing2020

Approaches for determining cardiac bidomain conductivity values: progress and challenges.

Barbara M Johnston, Peter R Johnston

Abstract readReview
In one paragraph

Review in Medical & biological engineering & computing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Barbara M JohnstonSchool of Environment and Science, and Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia. Barbara.Johnston@griffith.edu.au.ORCID http://orcid.org/0000-0001-5889-8501
Peter R JohnstonSchool of Environment and Science, and Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.

Funding

A New Approach for Measurement of Electrical Conductivities of Cardiac TissuesR03EB029625 · NIBIB · UNIVERSITY OF UTAH · PI DOSDALL, DEREK J, JOHNSTON, PETER · 2020 to 2021
$155k
NIBIB NIH HHS R03 EB029625NIH HHS R03EB029625
6 · The paper itself

Abstract

Modelling the electrical activity of the heart is an important tool for understanding electrical function in various diseases and conduction disorders. Clearly, for model results to be useful, it is necessary to have accurate inputs for the models, in particular the commonly used bidomain model. However, there are only three sets of four experimentally determined conductivity values for cardiac ventricular tissue and these are inconsistent, were measured around 40 years ago, often produce different results in simulations and do not fully represent the three-dimensional anisotropic nature of cardiac tissue. Despite efforts in the intervening years, difficulties associated with making the measurements and also determining the conductivities from the experimental data have not yet been overcome. In this review, we summarise what is known about the conductivity values, as well as progress to date in meeting the challenges associated with both the mathematical modelling and the experimental techniques. Graphical abstract Epicardial potential distributions, arising from a subendocardial ischaemic region, modelled using conductivity data from the indicated studies.

Indexed as

Models, CardiovascularMyocardial IschemiaComputer SimulationHeartHeart Conduction SystemHumansBidomain modelCardiac conductivity valuesElectrophysiologyHeartReview

Identifiers

PMID33089458
PMCPMC7755382

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.