Evidence map›Paper›PMID 33089378›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

Biopsy-proven Henoch-Schönlein purpura nephritis: a single center experience.

Eda Didem Kurt-Şükür, Thivya Sekar, Kjell Tullus

Open access · hybridAbstract read
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. Proanthocyanidins alleviate Henoch-Schönlein purpura by mitigating inflammation and oxidative stress through regulation of the TLR4/MyD88/NF-κB pathway.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Eda Didem Kurt-ŞükürDepartment of Pediatric Nephrology, Dr. Sami Ulus Children's Hospital, Ankara, Turkey.
Thivya SekarDepartment of Pediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Kjell TullusDepartment of Pediatric Pathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Kjell.Tullus@gosh.nhs.uk.ORCID 0000-0002-6234-6221
Great Ormond Street Hospital for Children NHS Foundation Trust · GBDr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge on normal progress and treatment of Henoch-Schönlein purpura nephritis (HSPN) is limited. This study reviews outcome, clinical, pathological, and therapeutic factors affecting the prognosis of HSPN patients.

methodsForty-nine children with biopsy-confirmed HSPN diagnosed between September 2008 and 2018 were included. Demographics, clinical and laboratory data, treatment, and outcome were recorded at the time of biopsy, 3, 6, 12, and 24 months and at last visit. Clinical outcome was graded according to Meadow's criteria.

resultsThe median age at time of biopsy was 10.1 years (IQR:5.7) and female/male ratio 24/25. At presentation, 40.8% of patients had nonnephrotic proteinuria, 18.4% nephrotic syndrome (NS), 4.1% nephritic syndrome (NephrS), and 36.7% NephrS+NS. There were 11 patients with an estimated glomerular filtration rate below 90 ml/min/1.73 m

conclusionA large proportion of patients continued to show signs of CKD at last follow-up while only a small proportion developed stage 5 CKD.

Indexed as

IgA VasculitisKidney Failure, ChronicNephritisRenal Insufficiency, ChronicAdolescentBiopsyChildChild, PreschoolFemaleHematuriaHumansMaleProteinuriaRetrospective StudiesChronic kidney diseaseHSPNImmunoglobulin A vasculitisOutcomePediatricsPrognosisTreatment

Identifiers

PMID33089378
PMCPMC8009786
OpenAlexW3093642549

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.