ArticleFrontiers in dentistry
Relationship between Parafunctional Habits and Salivary Biomarkers.
Article in Frontiers in dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Evaluation of the Stomatognathic System in Patients with Hearing Impairment and Cochlear Implants-A Pilot Study.Journal of clinical medicine · 2025Article
- Nordic Orofacial Test-Screening Protocol as a Tool for Assessment of Orofacial Dysfunction in Pediatric and Adult Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Does salivary cortisol serve as a potential biomarker for temporomandibular disorders in adults?BMC oral health · 2024Article
- Probable Bruxism and Psychological Issues among Dental Students in Serbia during the COVID-19 Pandemic.International journal of environmental research and public health · 2022Article
- Salivary biomarkers and temporomandibular disorders: A systematic review.National journal of maxillofacial surgeryReview
- [Salivary cortisol concentrations according to gender in the different stages of human development. A review of the literature].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesParafunctional habits, as one of the etiological factors of temporomandibular disorders (TMD), are an individual's response to increased stress. During stress and depression, biomarkers such as cortisol and salivary alpha-amylase (SAA) are secreted in the saliva. The present study aimed to investigate whether there is a correlation between salivary stress biomarkers and parafunctional habits. MATERIALS AND
methodsThirty-two cases, from May to September 2015, were selected based on two standard stress questionnaires, namely the depression anxiety stress Scale-21 (DASS-21) and the Beck Anxiety Inventory (BAI). Saliva samples were collected to examine the level of unstimulated salivary cortisol and SAA. The significance of the results was assessed via student's t-test and Mann-Whitney test (α=0.05).
resultsThe mean concentrations of cortisol and SAA in unstimulated saliva were significantly higher in the case group than in the control group (P=0.01 and 0.44, respectively). The mean scores of anxiety, stress, and depression were significantly higher in the case group than in the control group (P<0.05).
conclusionIt seems that the levels of salivary cortisol and SAA, as well as stress, anxiety, and depression scores, are higher in patients with parafunctional habits.
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