ArticleClocks & sleep2019
Steady-State Pupil Size Varies with Circadian Phase and Sleep Homeostasis in Healthy Young Men.
Article in Clocks & sleep, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Blue enriched light modulates pupil dilation induced by transcutaneous vagus nerve stimulation.Scientific reports · 2025Trial
- Sleuthing subjectivity: a review of covert measures of consciousness.Nature reviews. Neuroscience · 2025Review
- The Impact of Pupil Constriction on the Relationship Between Melanopic EDI and Melatonin Suppression in Young Adult Males.Journal of biological rhythms · 2024Article
- Article
- Importance of the locus coeruleus-norepinephrine system in sleep-wake regulation: Implications for aging and Alzheimer's disease.Sleep medicine reviews · 2022Review
- Deep learning-based pupil model predicts time and spectral dependent light responses.Scientific reports · 2021Article
- Time-Varying Light Exposure in Chronobiology and Sleep Research Experiments.Frontiers in neurology · 2021Review
- PupilEXT: Flexible Open-Source Platform for High-Resolution Pupillometry in Vision Research.Frontiers in neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pupil size informs about sympathovagal balance as well as cognitive and affective processes, and perception. It is also directly linked to phasic activity of the brainstem locus coeruleus, so that pupil measures have gained recent attention. Steady-state pupil size and its variability have been directly linked to sleep homeostasis and circadian phase, but results have been inconsistent. Here, we report robust changes in steady-state pupil size during 29 h of continuous wakefulness in healthy young men (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.