Evidence map›Paper›PMID 33089139›Full record

ArticleKidney medicine

Peritoneal Dialysis and Mortality, Kidney Transplant, and Transition to Hemodialysis: Trends From 1996-2015 in the United States.

Nidhi Sukul, Purna Mukhopadhyay, Douglas E Schaubel, Jeffrey Pearson, Marc Turenne, Rajiv Saran, Bruce M Robinson, Ronald L Pisoni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Shared Decision-Making for a Dialysis Modality.Kidney international reports · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nidhi SukulUniversity of Michigan, Ann Arbor, MI.
Purna MukhopadhyayArbor Research Collaborative for Health, Ann Arbor, MI.
Douglas E SchaubelArbor Research Collaborative for Health, Ann Arbor, MI.
Jeffrey PearsonArbor Research Collaborative for Health, Ann Arbor, MI.
Marc TurenneArbor Research Collaborative for Health, Ann Arbor, MI.
Rajiv SaranUniversity of Michigan, Ann Arbor, MI.
Bruce M RobinsonArbor Research Collaborative for Health, Ann Arbor, MI.
Ronald L PisoniArbor Research Collaborative for Health, Ann Arbor, MI.
Arbor Research Collaborative for Health · USUniversity of Michigan–Ann Arbor · USVA Ann Arbor Healthcare System · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
NCATS NIH HHS UL1 TR002240NLM NIH HHS HHSN276201400001C
6 · The paper itself

Abstract

RATIONALE &

objectiveTransitions between dialysis modalities can be disruptive to care. Our goals were to evaluate rates of transition from peritoneal dialysis (PD) to in-center hemodialysis (HD), mortality, and transplantation among incident PD patients in the US Renal Data System from 1996 to 2015 and identify factors associated with these outcomes. STUDY

designObservational registry-based retrospective cohort study. SETTING &

participantsMedicare patients incident to end-stage renal disease (ESRD) from January 1, 1996, through December 31, 2011 (for adjusted analyses; through December 31, 2014, for unadjusted analyses), and treated with PD 1 or more days within 180 days of ESRD incidence (n = 173,533 for adjusted analyses; n = 219,787 for unadjusted analyses). EXPOSURE & PREDICTORS: Exposure: 1 or more days of PD. Predictors: patient- and facility-level characteristics obtained from Centers for Medicare & Medicaid Services Form 2728 and other data sources. OUTCOMES: Patients were followed up for 3 years until transition to in-center HD, death, or transplantation. ANALYTICAL APPROACH: Multivariable Cox regression was used to estimate hazards over time and associations with predictors.

resultsCompared with earlier cohorts, recent incident PD patient cohorts had lower rates of death (48% decline) and transition to in-center HD (13% decline). Among many other findings, we found that: (1) rates of transition to in-center HD and death were lowest in the 2008 to 2011 cohort, (2) longer time receiving PD was associated with higher mortality risk but lower risk for transition to in-center HD, and (3) larger PD programs (≥25 vs ≤6 patients) displayed lower risks for death and transition to in-center HD. LIMITATIONS: Data collected on Form 2728 are only at the time of ESRD incidence and do not provide information at the time of transition to in-center HD, death, or transplantation.

conclusionsRates of transition from PD to in-center HD and death rates for PD patients decreased over time and were lowest in PD programs with 25 or more patients. Implications of the observed improved technique survival warrant further investigation, focusing on modifiable factors of center-level performance to create opportunities for improved patient outcomes.

Indexed as

hemodialysismortalityPeritoneal dialysistransitions

Identifiers

PMID33089139
PMCPMC7568078
OpenAlexW3048319971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.