Evidence map›Paper›PMID 33088537›Full record

ArticleClinical case reports2020

Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy.

Istvan Bodi, Ellen Merete Hagen, Gordon Thorpe Ingle, Michael P Lunn

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Istvan BodiClinical Neuropathology King's College Hospital NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0002-2533-4758
Ellen Merete HagenAutonomic Unit National Hospital for Neurology and Neurosurgery London UK.ORCID https://orcid.org/0000-0002-6925-6747
Gordon Thorpe IngleNeurology Department Whipps Cross University Hospital London UK.
Michael P LunnCentre for Neuromuscular Disease National Hospital for Neurology and Neurosurgery London UK.
National Hospital for Neurology and Neurosurgery · GBKing's College Hospital NHS Foundation Trust · GBWhipps Cross University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 46-year-old male had 11-year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α-synuclein immunoreactive Lewy bodies confirming the diagnosis of premanifesting Parkinson's disease (PD). PNS involvement in PD is underappreciated.

Indexed as

autonomic dysfunctionLewy body diseasemultiple system atrophyneurodegenerationParkinson's diseaseα‐synuclein

Identifiers

PMID33088537
PMCPMC7562892
OpenAlexW3039564631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.