Evidence map›Paper›PMID 33088501›Full record

ArticleJournal of animal science and biotechnology2020

Modulations of genes related to gut integrity, apoptosis, and immunity underlie the beneficial effects of

Kosar Gharib-Naseri, Juliano Cesar de Paula Dorigam, Kiran Doranalli, Sarbast Kheravii, Robert A Swick, Mingan Choct, Shu-Biao Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Animals : an open access journal from MDPI · 2026
    Review
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  4. Article
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  6. Gut Microbiota Modulation in Asthma-An In Vitro Study.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Effects ofFrontiers in immunology · 2025
    Article
  10. Heliyon · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. ProbioticMicroorganisms · 2023
    Article
  18. Article
  19. Dietary Use of Methionine Sources andAnimals : an open access journal from MDPI · 2022
    Article
  20. A Novel ProbioticMicrobiology spectrum · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kosar Gharib-NaseriSchool of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.
Juliano Cesar de Paula DorigamEvonik Nutrition & Care GmbH, 10-B226, Rodenbacher Chaussee 4, 63457 Hanau-Wolfgang, Germany.
Kiran DoranalliEvonik Nutrition & Care GmbH, 10-B226, Rodenbacher Chaussee 4, 63457 Hanau-Wolfgang, Germany.
Sarbast KheraviiSchool of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.
Robert A SwickSchool of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.
Mingan ChoctUniversity of New England, Armidale, NSW 2351 Australia.
Shu-Biao WuSchool of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.ORCID 0000-0002-1790-6015
University of New England · AUEvonik (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ban of in-feed antimicrobial additives has negatively affected the poultry industry by causing necrotic enteritis (NE) to emerge in the flocks. Alternatives such as

methodsIn both experiments, 480 day-old mix-sexed Ross-308 broilers were arranged in a 2 × 2 factorial arrangement of treatments. In experiment 1, the factors were NE challenge (yes or no) and probiotic (yes or no). In experiment 2, the factors were dietary crude protein levels (standard or reduced) and probiotic (yes or no) and were used under NE challenge condition. Oral administration of

resultsIn experiment 1, BA supplementation decreased caspase-3 (

conclusionThese findings suggest that supplementation of BA in broiler diets can improve gut health by modulation of genes related to the mucosal barrier, tight junction, and immunity in broilers challenged by unfavourable conditions such as NE challenge.

Indexed as

Bacillus amyloliquefaciensBroilerClostridium perfringensGene expressionNecrotic enteritisProbiotic

Identifiers

PMID33088501
PMCPMC7566066
OpenAlexW3092805456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.