Evidence map›Paper›PMID 33088479›Full record

ArticlePulmonary circulation

Right ventriculo-pulmonary arterial uncoupling and poor outcomes in pulmonary arterial hypertension.

Toshitaka Nakaya, Hiroshi Ohira, Takahiro Sato, Taku Watanabe, Masaharu Nishimura, Noriko Oyama-Manabe, Masaru Kato, Yoichi M Ito, Ichizo Tsujino

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Pulmonary ParenchymalJournal of clinical medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Toshitaka NakayaFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Hiroshi OhiraFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Takahiro SatoFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Taku WatanabeFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Masaharu NishimuraFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Noriko Oyama-ManabeDepartment of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan.
Masaru KatoDepartment of Rheumatology, Endocrinology and Nephrology, Hokkaido University, Sapporo, Japan.ORCID https://orcid.org/0000-0002-2023-6585
Yoichi M ItoDepartment of Statistical Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.
Ichizo TsujinoFirst Department of Medicine, Hokkaido University Hospital, Sapporo, Japan.
Hokkaido University Hospital · JPHokkaido University · JPThe Institute of Statistical Mathematics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right ventricular function critically affects the prognosis of patients with pulmonary arterial hypertension. We aimed to analyze the prognostic value of right ventricular indices calculated using magnetic resonance imaging and right heart catheterization metrics in pulmonary arterial hypertension. We retrospectively collected data from 57 Japanese patients with pulmonary arterial hypertension and 18 controls and calculated six indices of right ventricular function: two indices of contractility (end-systolic elastance calculated with right ventricular maximum pressure and with magnetic resonance imaging metrics); two indices of right ventricular-pulmonary arterial coupling (end-systolic elastance/arterial elastance calculated with the pressure method (end-systolic elastance/arterial elastance (P)) and with the volume method (end-systolic elastance/arterial elastance (V)); and two indices of right ventricular diastolic function (stiffness (β) and end-diastolic elastance). We compared the indices between controls and patients with pulmonary arterial hypertension and examined their prognostic role. In patients with pulmonary arterial hypertension, end-systolic elastance (right ventricular maximum pressure) was higher (pulmonary arterial hypertension 0.94 (median) vs control 0.42 (mmHg/mL),

Indexed as

magnetic resonance imagingpulmonary hypertensionpulmonary vasodilatorright ventricular function

Identifiers

PMID33088479
PMCPMC7543138
OpenAlexW3092152954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.