ReviewEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2020
The effect of exercise-based interventions on health-related quality of life and physical function in older patients with cancer receiving medical antineoplastic treatments: a systematic review.
Review in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Impact of physical activity and exercise training on health-related quality of life in older adults: an umbrella review.GeroScience · 2025Pooled it
- The effect of non-pharmacological interventions on cognitive function in cancer: an overview of systematic reviews.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Influence of physical exercise on health improvement in older adult cancer patients: a systematic review.Frontiers in public health · 2025Pooled it
- A pilot randomized controlled trial comparing the feasibility and preliminary effects of different forms of exercise-related social support for older adult survivors of cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Pilot study of an inpatient physical activity intervention for older adults treated intensively for acute myeloid leukemia.Blood advances · 2025Trial
- A pilot randomized controlled trial of a virtual peer-support exercise intervention for female older adults with cancer.BMC geriatrics · 2024Trial
- Effects of a 12-Week Multimodal Exercise Intervention Among Older Patients with Advanced Cancer: Results from a Randomized Controlled Trial.The oncologist · 2022Trial
- Movement-Based Interventions in Pre-Frail and Frail Older Adults: An Integrative Review of Clinical, Digital, and Implementation Evidence.Clinical interventions in aging · 2026Review
- Oncology nurses' knowledge, perceptions, and perceived barriers related to discussing physical activity with patients with cancer, including older adults.BMC nursing · 2025Article
- Article
- A Case Control Study Examining the Patterns and Predictors of Referral to Cancer Rehabilitation at Canada's Largest Comprehensive Cancer Centre.Cancer medicine · 2025Article
- Review
- Development and feasibility of an exercise therapy intervention for older women with advanced epithelial ovarian cancer referred to neoadjuvant chemotherapy prior to possible interval debulking surgery.Gynecologic oncology reports · 2024Article
- Impact of rehabilitation unit-based physical activity therapy versus symptomatic supportive treatment on older patients with advanced cancer: a non-randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Article
- Correlates and participation in community-based exercise programming for cancer patients before and during COVID-19.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Harms of exercise training in patients with cancer undergoing systemic treatment: a systematic review and meta-analysis of published and unpublished controlled trials.EClinicalMedicine · 2023Article
- Piloting HealthScore: Feasibility and acceptability of a clinically integrated health coaching program for people living with cancer.Cancer medicine · 2023Article
- Article
- Impact of the COVID-19 pandemic on physical activity among older adults with cancer in a central Canadian province: Results from a survey study.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Older patients with cancer are underrepresented in trials investigating the effect of exercise therapy. The aim of this systematic review was to investigate the effect of exercise therapy during medical antineoplastic treatment in older patients (≥ 65 years) with cancer. A systematic review following the Cochrane guidelines was performed. Randomized controlled trials were identified through a systematic literature search in MEDLINE, EMBASE, CENTRAL, and CINAHL up to December 2019. Study selection was performed independently by two reviewers. Four randomized controlled trials published between 2014 and 2019 were included comprising a total of 412 participants. Most participants were diagnosed with breast, prostate or colorectal cancer. The studies were characterized by large differences in design, interventions and outcomes, which prevented meta-analyses. The interventions ranged from 4 weeks to 12 months and involved both supervised and unsupervised exercise programs. Some evidence of beneficial effects from the interventions were documented on physical function, muscle strength, physical activity and cognitive function. No evidence of effects was found for health-related quality of life, aerobic capacity, body composition, cancer-related symptoms and side effects, or for any clinical outcomes. No adverse events were reported. Exercise therapy seems to be safe and feasible in older patients with cancer. However, due to a limited number of studies, small sample sizes and heterogeneity across study design, the effects of exercise in older patients with cancer receiving medical antineoplastic treatment are inconclusive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.