Evidence map›Paper›PMID 33088245›Full record

ArticleDose-response : a publication of International Hormesis Society

Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement.

Ruhollah Ghahramani-Asl, Pejman Porouhan, Mohammad Mehrpouyan, James S Welsh, Edward J Calabrese, Rachna Kapoor, Gaurav Dhawan, Seyed Alireza Javadinia

Open access · goldAbstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ruhollah Ghahramani-AslDepartment of Medical Physics and Radiation Sciences, Faculty of Paramedicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Pejman PorouhanDepartment of Radiation Oncology, Vasei Educational Hospital, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Mohammad MehrpouyanDepartment of Medical Physics and Radiation Sciences, Faculty of Paramedicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.
James S WelshLoyola University Chicago, Edward Hines Jr., VA Hospital, Stritch School of Medicine, Department of Radiation Oncology, Maywood, IL, USA.
Edward J CalabreseDepartment of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA.ORCID https://orcid.org/0000-0002-7659-412X
Rachna KapoorSaint Francis Hospital and Medical Center, Hartford, CT, USA.
Gaurav DhawanMedSurg Urgent Care, Gilbertsville, PA, USA.ORCID https://orcid.org/0000-0003-0511-7323
Seyed Alireza JavadiniaCellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.ORCID https://orcid.org/0000-0003-2467-837X
Sabzevar University of Medical Sciences · IRLoyola University Chicago · USSaint Francis University · USUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTo assess the feasibility of a treatment planning system in localizing, contouring, and targeting lung lesions along with an evaluation of volume indices of lung involvement in patients with COVID-19 pneumonia.

methodsWe evaluated 10 patients with PCR-confirmed COVID-19 pneumonia. The CT images were imported into the ISOgray® treatment planning system to anatomically define and contour the volumes of the pulmonary lesions, the lungs, and other nearby organs.

resultsThe ratio of lung lesion volume to lung volume in this study was 0.11 ± 0.13 (11.13%). The highest mean biosynthesis ratio of lung lesions was 0.36. The ratio of lesion volume in the left lung of patients with the highest volume of involvement, was 0.44, and the ratio of lesion volume in the right lung of these patients was 0.27 (approximately 1.5 times more in the left lung than the right lung). On average, CTDIvol and DLP for all patients studied in our study were 11.22 ± 2.47 mGy and 354.20 ± 65.11 mGy.cm.

conclusionWe reported the feasibility of using a treatment planning system in localizing COVID-19 pulmonary lesions and its validity in the volumetric assessment of infected lung regions.

Indexed as

3 dimensional (3D) conformal radiation therapyacute respiratory distress syndrome (ARDS)COVID-19low dose radiotherapySARS-CoV-2treatment planning system

Identifiers

PMID33088245
PMCPMC7545774
OpenAlexW3091188955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.