ReviewTropical medicine and health2020
Prevalence of vertical HIV infection and its risk factors among HIV exposed infants in East Africa: a systematic review and meta-analysis.
Review in Tropical medicine and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Magnitude and risk factors of mother-to-child transmission of HIV among HIV-exposed infants after Option B+ implementation in Ethiopia: a systematic review and meta-analysis.AIDS research and therapy · 2024Pooled it
- Unintended pregnancy among women living with HIV and its predictors in East Africa, 2024. A systematic review and meta-analysis.PloS one · 2024Pooled it
- Strikes of physicians and other health care workers in sub-Saharan African countries: a systematic review.Frontiers in public health · 2024Pooled it
- Time-Trend, Regional and National Prevalence of Vertical Transmission of HIV-1 in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Journal of primary care & community healthPooled it
- Risk Factors for Vertical Transmission of Human Immunodeficiency Virus in Angola: A Case-Control Study.Portuguese journal of public health · 2026Review
- Maternal and infant predictors of early mother-to-child transmission among HIV-exposed infants in the Karamoja region, Northeastern Uganda 2020-2023, a retrospective cross-sectional study.BMC infectious diseases · 2026Article
- Predicting early infant diagnosis (EID) results for HIV exposed infants in a resource-limited setting using machine learning models: evidence from Amhara Public Health Institute data (2024/2025).BMC infectious diseases · 2026Article
- Identifying individual, community and country-level determinants of poor knowledge of mother-to-child transmission of HIV among women in sub-Saharan Africa: spatial and multilevel analysis.SAGE open medicine · 2026Article
- Predictors of HIV Vertical Transmission in Exposed Infants in Northwest, Ethiopia: A Retrospective Cohort Study.Health science reports · 2026Article
- Prevalence and factors associated with sero-conversion among HIV exposed infants receiving care at Lira regional referral hospital in Lira City: a cross-sectional study.BMC pediatrics · 2025Article
- HIV vertical transmission linked to virological failure in pregnant women on ART.AIDS research and therapy · 2025Article
- Incidence and predictors of pregnancy among reproductive-age women in an ART clinic of public health facilities in Arsi zone, southeastern ethiopia: a five-year retrospective cohort study.BMC women's health · 2025Article
- HIV and Pregnancy: Navigating Complex Decision Making and Preventing Perinatal Transmission.Current HIV/AIDS reports · 2025Review
- Adherence, perceptions and knowledge of an HIV PMTCT programme: A mother-baby pair study.Southern African journal of HIV medicine · 2025Article
- Risk factors of under-five and infant mortality: An umbrella review of systematic reviews and meta-analyses.Journal of global health · 2024Review
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- Article
- Effect of Dolutegravir-Based First-Line Antiretroviral Therapy on Mother-to-Child Transmission of HIV Among HIV-Exposed Infants in Ethiopia: a Before-and-After Study.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Positivity rate, trend and associated risk factors of mother-to-child transmission of HIV among HIV-exposed infants.BMC pediatrics · 2023Article
- Incidence of HIV Infection among HIV-Exposed Iinfants at Gondar University Hospital from 2019-2021: A Prospective Cohort Study.Ethiopian journal of health sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman immunodeficiency virus (HIV) is one of the most important global health problems. More than one and half million of children are living with HIV in the world, and majority of them are found in sub-Saharan Africa. There are primary fragmented study findings, and no review was conducted with regard to vertical HIV infection in East Africa. Therefore, this review aimed to assess the prevalence of vertical HIV infection and its risk factors among HIV-exposed infants in East Africa. MAIN BODY: Eligible studies were retrieved by relevant search terms in CINHAL, Pub-MED, Google Scholar, EMBASE, Web of Science, SCOPUS, Cochrane, African Journals Online databases, and Ethiopian University research repositories. Data were extracted with Microsoft Excel and analyzed with Stata version 11 software. The random effect model was used to estimate the pooled prevalence of vertical HIV infection in East Africa. The variation between studies was quantified with an
conclusionsThe pooled prevalence of the mother to child transmission of HIV is way more than the desired target of the World Health Organization, which is less than 5% in breastfeeding populations. Thus, strengthening the prevention of vertical HIV transmission, promotion of exclusive breastfeeding, timely initiation of ART prophylaxis for HIV exposed infants, encouragement of hospital delivery, and the start of ART at the time of diagnosis of every HIV-positive person may all reduce the transmission of vertical HIV infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.