ReviewClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology2020
Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk.
Review in Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effect of Growth Rate during Infancy on the Risk of Developing Obesity in Childhood: A Systematic Literature Review.Nutrients · 2021Pooled it
- Baby-Feed Pilot Trial for Improving Diet and Weight Gain in Infants and Toddlers.Maternal and child health journal · 2026Trial
- Longitudinal assessments of child growth: A six-year follow-up of a cluster-randomized maternal education trial.Clinical nutrition (Edinburgh, Scotland) · 2021Trial
- Caregiver Feeding Practices and Late-Preschool BMI-for-Age z-Score Trajectories Among WIC-Enrolled Children: A National Longitudinal Study.Nutrients · 2026Article
- Changes in obesity and waist circumference in children and parents during the COVID-19 pandemic.Scientific reports · 2026Observational
- Targeted proteomics reveal association between maternal biomarkers and child body weight in the first year of life.Journal of the Endocrine Society · 2026Article
- Childhood body mass index trajectories and risk of overweight and obesity in young adulthood: a population-based prospective cohort study.European journal of pediatrics · 2026Article
- Rapid weight gain in first 2 years of life and BMI trajectories from 3 to <10 years: a population-based longitudinal study of 1.7 million Brazilian children.Lancet regional health. Americas · 2026Article
- Multidimensional factors associated with childhood obesity severity in southern China: a cross-sectional study.Frontiers in nutrition · 2026Article
- Iron Content and Nutritional Quality of Commercial Complementary Baby Foods Available in Australia.Journal of nutrition and metabolism · 2026Article
- Fluid intake in term and preterm infants exposed to maternal diabetes.Academia nutrition and dietetics · 2026Article
- Interaction of intrauterine Zika virus exposure on the relationship between body adiposity and dyslipidemia in school-aged children.Frontiers in pediatrics · 2026Article
- Early-Life Nutritional Determinants of Pediatric MASLD.Nutrients · 2025Review
- Association between Maternal Exposure to Per- and Polyfluoroalkyl Substances and Childhood Growth Trajectories up to 4 Years of Age: The Japan Environment and Children's Study.Environmental science & technology · 2025Article
- Life-long body mass index trajectories and cardiometabolic biomarkers-the Danish diet, cancer, and health-next generations cohort.International journal of obesity (2005) · 2025Article
- Differences in growth trajectories in breastfed HIV-exposed uninfected and HIV-unexposed infants in Kenya: An observational cohort study.PLoS medicine · 2025Observational
- Early-Life Exposure to Organic Chemical Pollutants as Assessed in Primary Teeth and Cardiometabolic Risk in Mexican American Children: A Pilot Study.International journal of environmental research and public health · 2025Article
- Association between placental epigenetic age acceleration and early postnatal growth patterns.Scientific reports · 2025Article
- Inverse relationship between serum carotenoid levels and obesity prevalence in children and adolescents: a nationwide cross-sectional analysis.BMC pediatrics · 2025Article
- Development of Machine Learning-Based Risk Prediction Models to Predict Rapid Weight Gain in Infants: Analysis of Seven Cohorts.JMIR public health and surveillance · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic changes in body weight have long been recognized as important indicators of risk for human health. Many population-based observational studies have shown that rapid weight gain during infancy, including a catch-up growth phenomenon or adiposity rebound in early childhood, predisposes a person to the development of obesity, type 2 diabetes, and cardiovascular diseases later in life. However, a consensus has not been established regarding which period of weight gain contributes to future risks. This review evaluates recent evidence on the relationship between early rapid growth and future obesity and cardiometabolic risk, with a focus on the differential significance of rapid weight gain in infancy and early childhood. Although there is a need for attention to childhood growth during early infancy before 1 yr of age as it may be related to future obesity, emerging evidence strongly suggests that toddlers showing an increase in body mass index (BMI) before 3 yr of age, a period normally characterized by decreased BMI, are prone to developing later cardiometabolic risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.