Evidence map›Paper›PMID 33087782›Full record

ArticleScientific reports2020

Microstructural degeneration and cerebrovascular risk burden underlying executive dysfunction after stroke.

Michele Veldsman, Emilio Werden, Natalia Egorova, Mohamed Salah Khlif, Amy Brodtmann

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
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  5. Review
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  7. Article
  8. Executive Functions and Public Health: A Narrative Review.Iranian journal of public health · 2023
    Review
  9. Article
  10. Article
  11. Spatial orientation - a stable marker for vascular cognitive impairment?Cerebral circulation - cognition and behavior · 2023
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Michele VeldsmanDepartment of Experimental Psychology, University of Oxford, New Radcliffe House, Radcliffe Observatory Quarter, Oxford, OX2 6GG, UK. michele.veldsman@psy.ox.ac.uk.
Emilio WerdenThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Natalia EgorovaThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Mohamed Salah KhlifThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Amy BrodtmannThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Florey Institute of Neuroscience and Mental Health · AUUniversity of Melbourne · AUUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Executive dysfunction affects 40% of stroke patients, but is poorly predicted by characteristics of the stroke itself. Stroke typically occurs on a background of cerebrovascular burden, which impacts cognition and brain network structural integrity. We used structural equation modelling to investigate whether measures of white matter microstructural integrity (fractional anisotropy and mean diffusivity) and cerebrovascular risk factors better explain executive dysfunction than markers of stroke severity. 126 stroke patients (mean age 68.4 years) were scanned three months post-stroke and compared to 40 age- and sex-matched control participants on neuropsychological measures of executive function. Executive function was below what would be expected for age and education level in stroke patients as measured by the organizational components of the Rey Complex Figure Test, F(3,155) = 17, R

Indexed as

Executive FunctionNerve DegenerationAgedAnisotropyCognitionDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedNerve NetRisk FactorsSeverity of Illness IndexStrokeWhite Matter

Identifiers

PMID33087782
PMCPMC7578057
OpenAlexW3094404927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.