Evidence map›Paper›PMID 33087745›Full record

ArticleScientific reports2020

Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents.

Lucas N Solano, Grady L Nelson, Conor T Ronayne, Shirisha Jonnalagadda, Sravan K Jonnalagadda, Kaija Kottke, Robert Chitren, Joseph L Johnson, Manoj K Pandey, Subash C Jonnalagadda and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Synthesis,RSC advances · 2024
    Article
  3. Research and development ofRSC medicinal chemistry · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Molecular Mechanisms of Canine Osteosarcoma Metastasis.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lucas N SolanoIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Grady L NelsonIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Conor T RonayneIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Shirisha JonnalagaddaIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Sravan K JonnalagaddaIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Kaija KottkeDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, 55812, USA.
Robert ChitrenDepartment of Chemistry and Biochemistry, Rowan University, Glassboro, NJ, 08028, USA.
Joseph L JohnsonDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, 55812, USA.
Manoj K PandeyDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, 08103, USA.
Subash C JonnalagaddaDepartment of Chemistry and Biochemistry, Rowan University, Glassboro, NJ, 08028, USA.
Venkatram R MereddyIntegrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA. vmereddy@d.umn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel N-phenylindazole based diarylureas have been designed, synthesized and evaluated as potential anticancer agents. In vitro cell viability studies of these derivatives illustrate good potency with IC

Indexed as

AmidesAnimalsAntineoplastic AgentsCell Line, TumorDisease Models, AnimalDose-Response Relationship, DrugDrug StabilityHumansMiceNeoplasmsNeoplasm TransplantationSolubilityUreaAmidesAntineoplastic AgentsUrea

Identifiers

PMID33087745
PMCPMC7578069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.