Trial reportThorax2020
Psychological outcomes of low-dose CT lung cancer screening in a multisite demonstration screening pilot: the Lung Screen Uptake Trial (LSUT).
Trial report in Thorax, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02558101 (Randomised Controlled Trial to Test Novel Invitation Methods and Materials Targeted to Increase Informed Uptake of Lung Cancer Screening in Individuals at High Risk of Lung Cancer), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomised Controlled Trial to Test Novel Invitation Methods and Materials Targeted to Increase Informed Uptake of Lung Cancer Screening in Individuals at High Risk of Lung Cancer
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Participant factors associated with psychosocial impacts of lung cancer screening: A systematic review.Cancer medicine · 2024Pooled it
- Interactions between upper respiratory microbiota and psychological distress in pulmonary nodule patients: a retrospective nested case-control study based on machine learning and exploratory mediation analysis.International journal of surgery (London, England) · 2025Article
- Structured narrative review on lung cancer screening: current evidence, clinical practice implications and implementation insights from a multidisciplinary task force and patient representatives.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Single-Round LDCT Screening in Men Aged ≥ 70 Years: Prevalence of Pulmonary Nodules and Lung Cancer Detection.Cancers · 2025Article
- Patients' experiences of, and psychological responses to, surveillance for pulmonary nodules detected through lung cancer screening.BMJ open respiratory research · 2025Article
- Cigarette Use, Lung Cancer Screening Eligibility and Completion Among Persons With Poor Mental Health.Cancer medicine · 2025Article
- Comparative long-term prognosis of early surgery and surgery after surveillance for patients with ground-glass nodule adenocarcinomas.Scientific reports · 2024Article
- Screening for lung cancer using thin-slice low-dose computed tomography in southwestern China: a population-based real-world study.Thoracic cancer · 2024Article
- Assessment of preoperative anxiety and depression in patients with pulmonary ground-glass opacities: Risk factors and postoperative outcomes.Frontiers in surgery · 2023Article
- Case report: Targeted sequencing facilitates the diagnosis and management of rare multifocal pure ground-glass opacities with intrapulmonary metastasis.Frontiers in oncology · 2023Article
- Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study.Health expectations : an international journal of public participation in health care and health policy · 2022Article
- European lung cancer screening: valuable trial evidence for optimal practice implementation.The British journal of radiology · 2022Article
- Should psychological distress be listed as a surgical indication for indeterminate pulmonary nodules: protocol for a prospective cohort study in real-world settings.Journal of thoracic disease · 2022Article
- The intervention effect of mental health knowledge integrated into ideological and political teaching on college students' employment and entrepreneurship mentality.Frontiers in psychology · 2022Article
- The psychological impact of esophageal cancer screening on anxiety and depression in China.Frontiers in psychiatry · 2022Article
- The person behind the nodule: a narrative review of the psychological impact of lung cancer screening.Translational lung cancer research · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPrevious studies of psychological burden in low-dose CT (LDCT) lung cancer screening trials may lack generalisability due to participation bias and control arms having elevated distress.
methodsCurrent and former smokers (n=787, aged 60-75) within a real-world screening demonstration pilot completed measures of lung cancer worry at three time points (T
resultsCompared with the community sample (T
conclusionPsychological distress was raised among high-risk individuals undergoing LDCT screening in a real-world setting, but overall differences were unlikely to be clinically meaningful. It will be critical to monitor the psychological impact of services longitudinally across diverse settings, including subgroups vulnerable to clinically elevated distress.
trial registrationThe Lung Screen Uptake Trial was registered prospectively with the International Standard Registered Clinical/soCial sTudy (ISRCTN) (Number: ISRCTN21774741) on 23 September 2015 and the National Institutes of Health ClinicalTrials.gov database (NCT02558101) on 22 September 2015.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.