Evidence map›Paper›PMID 33087520›Full record

ArticlemSphere2020

The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence Clostridioides difficile Clearance in Mice.

Sarah Tomkovich, Joshua M A Stough, Lucas Bishop, Patrick D Schloss

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Acidification-dependent suppression ofInfection and immunity · 2026
    Article
  2. Acidification-dependent suppression ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Journal of bacteriology · 2025
    Review
  6. Article
  7. The state of play of rodent models for the study ofJournal of medical microbiology · 2024
    Review
  8. Reviewing theMicroorganisms · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah TomkovichDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1638-5307
Joshua M A StoughDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-3488-4169
Lucas BishopDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Patrick D SchlossDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA pschloss@umich.edu.ORCID 0000-0002-6935-4275
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8M
NCATS NIH HHS UL1 TR002240NIAID NIH HHS U01 AI124255
6 · The paper itself

Abstract

The gut microbiota has a key role in determining susceptibility to

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBreedingClostridioides difficileClostridium InfectionsDisease Models, AnimalFecesFemaleGastrointestinal MicrobiomeMiceMice, Inbred C57BLRNA, Ribosomal, 16SAnti-Bacterial AgentsRNA, Ribosomal, 16S16S rRNAClostridioides difficileClostridium difficilemicrobial ecologymicrobiomemicrobiota

Identifiers

PMID33087520
PMCPMC7580958
OpenAlexW3093983715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.