Evidence map›Paper›PMID 33087478›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.

Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto, Noriyuki Sugo

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. DNA polymerase β suppresses somatic indels at CpG dinucleotides in developing cortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Akiko UyedaGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.
Kohei OnishiGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.
Teruyoshi HirayamaGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.
Satoko HattoriInstitute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470-1192, Japan.ORCID 0000-0002-1047-6454
Tsuyoshi MiyakawaInstitute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470-1192, Japan.ORCID 0000-0003-0137-8200
Takeshi YagiGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0002-6604-0318
Nobuhiko YamamotoGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0002-1916-932X
Noriyuki SugoGraduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan sugo@fbs.osaka-u.ac.jp.ORCID 0000-0001-5319-1603
The University of Osaka · JPFujita Health University · JPJapan Agency for Medical Research and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome stability is essential for brain development and function, as

Indexed as

DNA Breaks, Double-Stranded5-MethylcytosineAnimalsDendritesDNA-Binding ProteinsDNA MethylationDNA Polymerase betaFemaleHippocampusLearningMaleMemoryMiceMice, KnockoutMicroRNAsMitosis5-hydroxymethylcytosine5-MethylcytosineDNA-Binding ProteinsDNA Polymerase betaMicroRNAsMIRN29 microRNA, mouseProto-Oncogene ProteinsTET1 protein, mouseDNA demethylationDNA double-strand breakDNA repairhippocampal developmentlearning and memoryneuronal differentiation

Identifiers

PMID33087478
PMCPMC7672999
OpenAlexW3093781296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.