Evidence map›Paper›PMID 33087456›Full record

ArticleDiabetes2021

Adiponectin Promotes Maternal β-Cell Expansion Through Placental Lactogen Expression.

Liping Qiao, Sarah Saget, Cindy Lu, William W Hay, Gerard Karsenty, Jianhua Shao

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Serum Markers of Abnormal Placental Attachment in Pregnant Women.Bulletin of experimental biology and medicine · 2025
    Article
  7. Article
  8. Morfofunctional and Molecular Changes in Placenta and Peripheral Blood in Preeclampsia and Gestational Diabetes Mellitus.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Liping QiaoDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
Sarah SagetDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
Cindy LuDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
William W HayDepartment of Pediatrics, University of Colorado, Denver, CO.
Gerard KarsentyDepartment of Genetics and Development, Department of Medicine, Columbia University, New York, NY.
Jianhua ShaoDepartment of Pediatrics, University of California, San Diego, La Jolla, CA jishao@ucsd.edu.ORCID 0000-0002-3586-3602
University of California San Diego · USColumbia University · USUniversity of Colorado Denver · US

Funding

Hypoadiponectinemia and Gestational DiabetesR01DK113007 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jianhua Shao · 2018 to 2026
$3.5M
The maternal-fetal adiponectin differential and fetal fat depositionR01DK095132 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAO, JIANHUA · 2012 to 2021
$2.9M
NIDDK NIH HHS R01 DK095132NIDDK NIH HHS R01 DK113007
6 · The paper itself

Abstract

Hypoadiponectinemia is a risk factor of gestational diabetes mellitus (GDM). Our previous study reported that adiponectin gene knockout mice (

Indexed as

AdiponectinAnimalsCell LineCell ProliferationFemaleHumansInsulinInsulin-Secreting CellsIslets of LangerhansMiceMice, KnockoutPlacentaPlacental LactogenPregnancyReceptors, AdiponectinTrophoblastsAdiponectinInsulinPlacental LactogenReceptors, Adiponectin

Identifiers

PMID33087456
PMCPMC7881845
OpenAlexW3093978634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.