Evidence map›Paper›PMID 33087446›Full record

ArticleThe Journal of biological chemistry2020

Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness.

Ridim D Mote, Jyoti Yadav, Surya Bansi Singh, Mahak Tiwari, Shinde Laxmikant V, Shivprasad Patil, Deepa Subramanyam

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clathrin Light Chains: Not to Be Taken so Lightly.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ridim D MoteNational Centre for Cell Science, SP Pune University Campus, Pune, India; Babasaheb Ambedkar Marathwada University, Aurangabad, India; Applied Parasitology Research Laboratory, Department of Zoology, JES College, Jalna, India.
Jyoti YadavIndian Institute of Science Education and Research, Pune, India.
Surya Bansi SinghNational Centre for Cell Science, SP Pune University Campus, Pune, India; Savitribai Phule Pune University, Pune, India.
Mahak TiwariNational Centre for Cell Science, SP Pune University Campus, Pune, India; Savitribai Phule Pune University, Pune, India.
Shinde Laxmikant VBabasaheb Ambedkar Marathwada University, Aurangabad, India; Applied Parasitology Research Laboratory, Department of Zoology, JES College, Jalna, India.
Shivprasad PatilIndian Institute of Science Education and Research, Pune, India. Electronic address: s.patil@iiserpune.ac.in.
Deepa SubramanyamNational Centre for Cell Science, SP Pune University Campus, Pune, India. Electronic address: deepa@nccs.res.in.
National Centre for Cell Science · INDr. Babasaheb Ambedkar Marathwada University · INIndian Institute of Science Education and Research Pune · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mouse embryonic stem cells (mESCs) display unique mechanical properties, including low cellular stiffness in contrast to differentiated cells, which are stiffer. We have previously shown that mESCs lacking the clathrin heavy chain (

Indexed as

EndocytosisActin CytoskeletonActin Depolymerizing FactorsActinsAnimalsBridged Bicyclo Compounds, HeterocyclicCell DifferentiationCellular ReprogrammingClathrin Heavy ChainsElastic ModulusMiceMicroscopy, Atomic ForceMouse Embryonic Stem CellsPhosphorylationProfilinsRNA InterferenceActin Depolymerizing FactorsActinsBridged Bicyclo Compounds, HeterocyclicClathrin Heavy ChainsCLTC protein, humanlatrunculin APfn1 protein, mouseProfilinsRNA, Small InterferingThiazolidinesactinactin cytoskeletonatomic force microscopybiophysicsclathrinclathrin heavy chaincofilinembryonic stem cellembryonic stem cellspluripotencyreprogrammingstiffnessYoung's modulus

Identifiers

PMID33087446
PMCPMC7864080
OpenAlexW3094419748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.