Evidence map›Paper›PMID 33087368›Full record

ArticleBMJ open2020

Expanding access to non-communicable disease care in rural Malawi: outcomes from a retrospective cohort in an integrated NCD-HIV model.

Emily B Wroe, Noel Kalanga, Elizabeth L Dunbar, Lawrence Nazimera, Natalie F Price, Adarsh Shah, Luckson Dullie, Bright Mailosi, Grant Gonani, Enoch P L Ndarama and 5 more

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Emily B WroePartners In Health, Neno, Malawi emwroe@gmail.com.ORCID 0000-0002-9152-9553
Noel KalangaDepartment of Health Systems and Policy, College of Medicine, Blantyre, Malawi.
Elizabeth L DunbarPartners In Health, Neno, Malawi.
Lawrence NazimeraMinistry of Health, Neno District Health Office, Ministry of Health, Neno, Malawi.
Natalie F PricePartners In Health, Boston, Massachusetts, USA.
Adarsh ShahPartners In Health, Boston, Massachusetts, USA.
Luckson DulliePartners In Health, Neno, Malawi.
Bright MailosiPartners In Health, Neno, Malawi.
Grant GonaniMinistry of Health, Neno District Health Office, Ministry of Health, Neno, Malawi.
Enoch P L NdaramaMinistry of Health, Neno District Health Office, Ministry of Health, Neno, Malawi.
George C TalamaPartners In Health, Neno, Malawi.
Gene BukhmanDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Lila KerrPartners In Health, Neno, Malawi.
Emilia ConnollyPartners In Health, Neno, Malawi.
Chiyembekezo KachimangaPartners In Health, Neno, Malawi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNon-communicable diseases (NCDs) account for one-third of disability-adjusted life years in Malawi, and access to care is exceptionally limited. Integrated services with HIV are widely recommended, but few examples exist globally. We report descriptive outcomes from an Integrated Chronic Care Clinic (IC3).

designThis is a retrospective cohort study.

settingThe study includes an HIV-NCD clinic across 14 primary care facilities in the rural district of Neno, Malawi.

participantsAll new patients, including 6233 HIV-NCD diagnoses, enrolled between January 2015 and December 2017 were included. This included 3334 patients with HIV (59.7% women) and 2990 patients with NCD (67.3% women), 10% overall under age 15 years.

interventionsPatients were seen at their nearest health centre, with a hospital team visiting routinely to reinforce staffing. Data were collected on paper forms and entered into an electronic medical record. PRIMARY AND SECONDARY OUTCOME MEASURES: Routine clinical measurements are reported at 1-year post-enrolment for patients with more than one visit. One-year retention is reported by diagnosis.

resultsNCD diagnoses were 1693 hypertension, 668 asthma, 486 epilepsy, 149 diabetes and 109 severe mental illness. By December 2018, 8.3% of patients with NCD over 15 years were also on HIV treatment. One-year retention was 85% for HIV and 72% for NCDs, with default in 8.4% and 25.5% and deaths in 4.0% and 1.4%, respectively. Clinical outcomes showed statistically significant improvement for hypertension, diabetes, asthma and epilepsy. Of the 1807 (80%) of patients with HIV with viral load results, 85% had undetectable viral load.

conclusionsThe IC3 model, built on an HIV platform, facilitated rapid decentralisation and access to NCD services in rural Malawi. Clinical outcomes and retention in care are favourable, suggesting that integration of chronic disease care at the primary care level poses a way forward for the large dual burden of HIV and chronic NCDs.

Indexed as

HIV InfectionsNoncommunicable DiseasesAdolescentFemaleHumansMalawiMaleRetrospective StudiesRural Populationcardiologydiabetes & endocrinologyepilepsyhealth services administration & managementHIV & AIDS

Identifiers

PMID33087368
PMCPMC7580053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.