ArticleScience advances2020
MCART1/SLC25A51 is required for mitochondrial NAD transport.
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Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.
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129citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
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Who cites it
129 citing papers in PubMed, 188 citations in OpenAlex.
- Remodeling of mitochondrial dynamics by metabolic pathways couples to oncogenic growth inScience advances · 2026Article
- Nicotinamide Mononucleotide Adenylyltransferase 1 and NADMetabolites · 2026Review
- SLC25A51 and mitochondrial NAD⁺ transport in acute myeloid leukemia: mechanisms, therapeutic potential, and translational perspectives.Human cell · 2026Review
- NAD Metabolism in Acute Myeloid Leukaemia: Biological Rationale and Therapeutic Opportunities.Nutrients · 2026Review
- Solute carrier transporters as metabolic gatekeepers in tumor-microenvironment crosstalk.Acta pharmacologica Sinica · 2026Review
- dCas9-metabolic enzyme fusions modulate global and locus-specific gene expression.bioRxiv : the preprint server for biology · 2026Article
- The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging.Aging cell · 2026Article
- Redox index and capacity analysis (RICA) reveals NAD biology changes in T cell responses in vitro and ex vivo.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- From the cytosol to the inner membrane: biogenesis of the mitochondrial carrier family.Protein science : a publication of the Protein Society · 2026Review
- Aspartate availability drives differential engagement of the malate-aspartate shuttle.Molecular cell · 2026Article
- SLC6A6 imports taurine into mitochondria to sustain mitochondrial translation and tumour growth.Nature metabolism · 2026Article
- Nicotinamide salvage is required for proliferation and sustaining self-renewal in undifferentiated embryonic stem cells.Stem cells (Dayton, Ohio) · 2026Article
- Receptor-Mitochondria Crosstalk in the Kynurenine Metabolic Pathway: Integrating Metabolomics and Clinical Mass Spectrometry.Antioxidants (Basel, Switzerland) · 2026Review
- Targeting miR-4653-3p/SLC25A51/SIRT3 axis to induce synthetic lethality in ARID1A-deficient colorectal cancer via blockade of DNA repair.Journal of translational medicine · 2026Article
- Mitochondrial NMNAT3 reduces amyloid aggregates inMitochondrial communications · 2026Article
- Berbamine sensitizes hepatocellular carcinoma to chemotherapy by inhibiting autophagyFrontiers in pharmacology · 2026Article
- Nicotinamide riboside enhances liver regeneration via the MCART1/ASB3 axis in obesity-compromised rats.Hepatology communications · 2026Article
- Long-term high-protein diet intake accelerates adipocyte senescence through macrophage CD38-mediated NADMolecular metabolism · 2026Article
- Changes in the brain [NADFrontiers in aging neuroscience · 2026Review
- SLC25A mitochondrial carriers as biomarkers and therapeutic targets of spaceflight-induced dysfunction: the ADP/ATP carrier (AAC3) as a structural case study.Journal of translational medicine · 2025Article
69 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 2 institutions in 1 country.
Nora KoryWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-5307-9021
Jelmi Uit de BosWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0002-8807-3284
Sanne van der RijtWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-6486-4674
Nevena JankovicWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-6076-0165
Miriam GüraWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.
Nicholas ArpWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-8709-0667
Izabella A PenaWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-5242-3724
Gyan PrakashWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0003-4725-9178
Sze Ham ChanWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0002-3235-0852
Tenzin KunchokWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0001-6603-4607
Caroline A LewisWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.ORCID 0000-0003-1787-5084
David M SabatiniWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA. sabatini@wi.mit.edu.ORCID 0000-0002-1446-7256
Whitehead Institute for Biomedical Research · USBroad Institute · US
Funding
Regulation of the mTOR Pathway By NutrientsR01CA103866 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2004 to 2021
$7.0MCell Growth Signaling in Cancer DevelopmentR01CA129105 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2008 to 2021
$5.9MNovel Components of the mTORC1 and mTORC2 PathwaysR37AI047389 · NIAID · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI SABATINI, DAVID M. · 2010 to 2019
$4.8MSubstrates and functions of the Sideroflexin mitochondrial transporter familyR00CA241332 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI KORY, NORA · 2021 to 2023
$669kSubstrates and functions of the Sideroflexin mitochondrial transporter familyK99CA241332 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI KORY, NORA · 2019 to 2020
$216kNCI NIH HHS K99 CA241332NCI NIH HHS R00 CA241332NCI NIH HHS R01 CA103866NCI NIH HHS R01 CA129105NIAID NIH HHS R37 AI047389
Abstract
The nicotinamide adenine dinucleotide (NAD
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.