Evidence map›Paper›PMID 33087326›Full record

ReviewDevelopment (Cambridge, England)2020

The developing heart: from

Benoit G Bruneau

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The role of geometry in morphogenesis.Development (Cambridge, England) · 2026
    Review
  2. Coordination of cardiogenesis in vivo and in vitro.Nature reviews. Molecular cell biology · 2026
    Review
  3. Article
  4. Article
  5. Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
  6. Mitochondrial non-energetic function and embryonic cardiac development.Frontiers in cell and developmental biology · 2024
    Review
  7. Cardiac Development and Animal Models of Congenital Heart Defects.Advances in experimental medicine and biology · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Benoit G BruneauGladstone Institutes, San Francisco, CA 94158, USA benoit.bruneau@gladstone.ucsf.edu.ORCID 0000-0002-0804-7597

Funding

Early Cardiac ProgenitorsR01HL114948 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI Benoit Gaetan Bruneau · 2013 to 2026
$7.5M
The Epigenetic Landscape of Heart DevelopmentUM1HL098179 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN, POLLARD, KATHERINE S. · 2015 to 2019
$4.7M
NHLBI NIH HHS R01 HL114948NHLBI NIH HHS UM1 HL098179
6 · The paper itself

Abstract

The heart is an essential organ with a fascinating developmental biology. It is also one of the organs that is most often affected in human disease, either during development or in postnatal life. Over the last few decades, insights into the development of the heart have led to fundamental new concepts in gene regulation, but also to genetic and mechanistic insights into congenital heart defects. In more recent years, the lessons learned from studying heart development have been applied to interrogating regeneration of the diseased heart, exemplifying the importance of understanding the mechanistic underpinnings that lead to the development of an organ.

Indexed as

AnimalsChromatinHeartHeart Defects, CongenitalHumansRegenerationTranscription FactorsChromatinTranscription FactorsCongenital heart diseaseGene regulationHeart developmentRegeneration

Identifiers

PMID33087326
PMCPMC7595695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.