ArticleBMC neurology2020
Extracranial metastases in secondary glioblastoma multiforme: a case report.
Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Multidisciplinary treatment is necessary in glioblastoma with extracerebral metastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Pooled it
- Bone metastasis from glioblastoma: a systematic review.Journal of neuro-oncology · 2022Pooled it
- Delayed Effect of Dendritic Cells Vaccination on Survival in Glioblastoma: A Systematic Review and Meta-Analysis.Current oncology (Toronto, Ont.) · 2022Pooled it
- Early extracranial dissemination with prolonged survival in IDH-wildtype glioblastoma: case study and comprehensive literature review.CNS oncology · 2026Review
- Extracranial Metastases in Glioblastoma, IDH-Wildtype: A Case Series.Diagnostics (Basel, Switzerland) · 2026Article
- High-Grade Glioma With Parotid Metastasis: A Case Report of Long-Term Treatment and Follow-Up.Cureus · 2025Article
- Metastatic glioblastoma to the lungs: a case report and literature review.CNS oncology · 2024Review
- Rare Case of Extracranial Metastases in a Patient with IDH-Mutant Glioblastoma.South Asian journal of cancer · 2023Article
- Systemic Metastasis of Pediatric Diffuse High-grade Astrocytoma: A Case Report.NMC case report journal · 2023Article
- Letter to the editor regarding "unusual extraneural metastasis of glioblastoma".Surgical neurology international · 2023Article
- A Case of Extracranial Metastasis of Glioblastoma Multiforme Seen on Bone Scintigraphy.Molecular imaging and radionuclide therapy · 2022Article
- Epileptogenesis and Tumorigenesis in Glioblastoma: Which Relationship?Medicina (Kaunas, Lithuania) · 2022Review
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- Article
- Glioblastoma multiforme with vertebral metastases: A case report.CNS neuroscience & therapeutics · 2022Article
- Cervical Lymph Node Metastases from Central Nervous System Tumors: A Systematic Review.Cancer management and research · 2022Review
- Article
- Glioblastoma Multiforme-A Look at the Past and a Glance at the Future.Pharmaceutics · 2021Review
- Tumor Associated Macrophages, as the Dominant Immune Cells, Are an Indispensable Target for Immunologically Cold Tumor-Glioma Therapy?Frontiers in cell and developmental biology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlioblastoma (GBM) is known for its devastating intracranial infiltration and its unfavorable prognosis, while extracranial involvement is a very rare event, more commonly attributed to IDH wild-type (primary) GBM evolution. CASE PRESENTATION: We present a case of a young woman with a World Health Organization (WHO) grade II Astrocytoma evolved to WHO grade IV IDH mutant glioblastoma, with subsequent development of lymphatic and bone metastases, despite the favorable biomolecular pattern and the stability of the primary brain lesion.
conclusionsOur case highlights that grade II Astrocytoma may evolve to a GBM and rarely lead to a secondary metastatic diffusion, which can progress quite rapidly; any symptoms referable to a possible systemic involvement should be carefully investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.