Evidence map›Paper›PMID 33086917›Full record

ArticleLupus2021

Multimorbidity among incident Finnish systemic lupus erythematosus patients during 2000-2017.

Simo Kariniemi, Vappu Rantalaiho, Lauri J Virta, Kari Puolakka, Tuulikki Sokka-Isler, Pia Elfving

Abstract read
In one paragraph

Article in Lupus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  4. Observational
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simo KariniemiSchool of Medicine, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0001-8355-0531
Vappu RantalaihoCentre for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland.
Lauri J VirtaResearch Department, Social Insurance Institution, Turku, Finland.
Kari PuolakkaTerveystalo Healthcare, Lappeenranta, Finland.
Tuulikki Sokka-IslerFaculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Pia ElfvingDepartment of Medicine, Kuopio University Hospital, Kuopio, Finland.ORCID https://orcid.org/0000-0002-9885-7242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to examine the risk of other morbidities among patients with systemic lupus erythematosus (SLE). A total of 1006 adult new-onset SLE patients were identified during 1.1.2000- 31.12.2014 from the register of Social Insurance Institution. For each case three general population controls matched according to age, sex and place of residence at the index day were sampled from the population register. Both groups were followed up from the index date until the end of 2017 or until death. The national register on specialized care was explored to gather broadly their 12 organ-specific morbidities, which were found among 91.2% of SLE patients and 66.7% of comparators. The rate ratio (RR) was elevated in almost all disease groups. Musculoskeletal, cardiovascular and genitourinary conditions were the most common comorbidities with RRs of 1.82 (1.68 to 1.97), 1.91 (1.76 to 2.08) and 1.91 (1.73 to 2.09), respectively. Men with SLE had a significantly higher risk for diseases of the genitourinary system and endocrine, nutritional and metabolic diseases compared to women with SLE. The risk of concurrent morbidities is essential to note in the care of SLE patients.

Indexed as

AdultAge FactorsCardiovascular DiseasesCase-Control StudiesEducational StatusFemaleFinlandHumansIncidenceLogistic ModelsLupus Erythematosus, SystemicMaleMiddle AgedMultimorbidityRegistriesRisk Factorscardiovascular diseasecomorbiditygendermorbiditySystemic lupus erythematosus

Identifiers

PMID33086917
PMCPMC7768886

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.