Evidence map›Paper›PMID 33086737›Full record

ReviewViruses2020

Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs.

Tanel Punga, Mahmoud Darweesh, Göran Akusjärvi

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Structural Insights into Human Adenovirus Type 4 Virus-Associated RNA I.International journal of molecular sciences · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Inhibition of PKR by Viruses.Frontiers in microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tanel PungaDepartment of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.ORCID 0000-0002-0561-367X
Mahmoud DarweeshDepartment of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.
Göran AkusjärviDepartment of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory, ocular and gastrointestinal diseases. To accomplish their efficient replication, HAdVs take an advantage of viral small non-coding RNAs (sncRNAs), which have multiple roles during the virus lifecycle. Three of the best-characterized HAdV sncRNAs; VA RNA, mivaRNA and MLP-TSS-sRNA will be discussed in the present review. Even though VA RNA has been extensively characterized during the last 60 years, this multifunctional molecule continues to surprise us as more of its structural secrets unfold. Likely, the recent developments on mivaRNA and MLP-TSS-sRNA synthesis and function highlight the importance of these sncRNA in virus replication. Collectively, we will summarize the old and new knowledge about these three viral sncRNAs with focus on their synthesis, structure and functions.

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanHEK293 CellsHeLa CellsHumansRNA, Small UntranslatedVirus ReplicationRNA, Small UntranslatedDicerhuman adenovirusmiRISCmivaRNAMLP-TSS-sRNAPKRsncRNAVA RNA

Identifiers

PMID33086737
PMCPMC7589676
OpenAlexW3094282869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.