Evidence map›Paper›PMID 33086730›Full record

ReviewCancers2020

Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer.

Marina Pavanello, Isaac Hy Chan, Amir Ariff, Paul Dp Pharoah, Simon A Gayther, Susan J Ramus

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. The Genetic and Molecular Analyses of Rare Candidate GermlineInternational journal of molecular sciences · 2026
    Article
  2. Double jeopardy: howFrontiers in cell and developmental biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. GermlineJournal of personalized medicine · 2024
    Article
  8. Article
  9. OvaPrint-A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  10. Review
  11. Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Rare Hereditary Gynecological Cancer Syndromes.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Marina PavanelloSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-4190-5554
Isaac Hy ChanSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Amir AriffSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Paul Dp PharoahStrangeways Research Laboratory, University of Cambridge, Cambridge CB1 8RN, UK.
Simon A GaytherCenter for Cancer Prevention and Translational Genomics, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.
Susan J RamusSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
UNSW Sydney · AUCedars-Sinai Medical Center · USUniversity of Cambridge · GB

Funding

The contribution of rare alleles to ovarian cancer in the populationR01CA178535 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAYTHER, SIMON ANDREW, PHAROAH, PAUL · 2013 to 2017
$3.0M
NCI NIH HHS R01 CA178535
6 · The paper itself

Abstract

A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the

Indexed as

ovarian cancer riskrare germline variantssusceptibility genes

Identifiers

PMID33086730
PMCPMC7589980
OpenAlexW3093053551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.