Evidence map›Paper›PMID 33086719›Full record

ArticleJournal of clinical medicine2020

Myocardial Infarction after Kidney Transplantation: A Risk and Specific Profile Analysis from a Nationwide French Medical Information Database.

Romain Didier, Hermann Yao, Mathieu Legendre, Jean Michel Halimi, Jean Michel Rebibou, Julien Herbert, Marianne Zeller, Laurent Fauchier, Yves Cottin

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Hypertension in kidney transplant recipients.World journal of transplantation · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Romain DidierDepartment of Cardiology, University Teaching Hospital Burgundy, 21000 Dijon, France.
Hermann YaoDepartment of Cardiology, University Teaching Hospital Burgundy, 21000 Dijon, France.
Mathieu LegendreDepartment of Nephrology, University Teaching Hospital Burgundy, 21000 Dijon, France.
Jean Michel HalimiDepartment of Nephrology, University Teaching Hospital of Trousseau and University François Rabelais University, 37000 Tours, France.
Jean Michel RebibouDepartment of Nephrology, University Teaching Hospital Burgundy, 21000 Dijon, France.
Julien HerbertDepartment of Cardiology, University Teaching Hospital of Trousseau and EA7505, University François Rabelais University, 37000 Tours, France.
Marianne ZellerPEC2 Research Team, EA 7460, Department of Health Sciences, University of Burgundy Franche Comté, 25000 Besançon, France.
Laurent FauchierDepartment of Cardiology, University Teaching Hospital of Trousseau and EA7505, University François Rabelais University, 37000 Tours, France.
Yves CottinDepartment of Cardiology, University Teaching Hospital Burgundy, 21000 Dijon, France.
Université de Tours · FRUniversité de Bourgogne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRenal transplant recipients have a high peri-operative risk for cardiovascular events. The post-transplantation period also carries a risk of myocardial infarction (MI). Coronary artery disease (CAD) is a leading cause of death in these patients. We aimed to assess the risk of MI, the specific morbidity profile of MI after transplantation as well as the long-term prognosis after MI in renal transplantation (RT) patients regarding cardiovascular (CV) death and all-cause death.

methodsFrom a French national medical information database, all of the patients seen in French hospitals in 2013 with at least 5-years follow-up were retrospectively identified and patients without transplantation but with previous dialysis at baseline were excluded. There were 17,526 patients with RT and 3,288,857 with no RT.

resultsAmong these patients, 1020 in the RT group (5.8%), and 93,320 in the non-RT group (2.8%) suffered acute MI during a median follow-up of 5.4 years. After multivariable adjustment, risk of MI was higher in RT patients than in non-RT patients (HR 1.45, IC 95% 1.35-1.55). The mean age was 59.5 years for transplant patients with MI, and 70.6 years for the reference population with MI (

conclusionsMI is not an uncommon complication after RT (incidence of around 5.8% after 5 years). RT is independently associated with a 45% higher risk of MI than in patients without RT, with a predominance of NSTEMI. MI in patients with RT is independently associated with a 15% higher risk of all-cause death than that in patients with MI and no RT.

Indexed as

all-cause of mortalitycardiovascular deathfollow ow-upmyocardial infarctionrenal transplant recipients

Identifiers

PMID33086719
PMCPMC7589663
OpenAlexW3093379546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.