ArticleJournal of clinical medicine2020
Relative Skeletal Muscle Mass Is an Important Factor in Non-Alcoholic Fatty Liver Disease in Non-Obese Children and Adolescents.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Body Composition Changes in Adolescents Who Underwent Bariatric Surgery: A Systematic Review and Meta-analysis.Current obesity reports · 2024Pooled it
- Sarcopenia in pediatric gastroenterology and hepatology: an updated review.Clinical and experimental pediatrics · 2026Article
- Sex Differences in Body Composition and MASLD in Children With Overweight and Obesity.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Unraveling the Metabolic Pathways Between Metabolic-Associated Fatty Liver Disease (MAFLD) and Sarcopenia.International journal of molecular sciences · 2025Review
- Association of ultrasound signs of sarcopenia with serum ferritin levels and hepatic indices like NFS and FIB-4 in NAFLD patients.BMC gastroenterology · 2025Article
- A bibliometric analysis of metabolic dysfunction-associated steatotic liver disease in children from 2004 to 2024.Frontiers in pediatrics · 2025Review
- Exploring non-invasive diagnostics and non-imaging approaches for pediatric metabolic dysfunction-associated steatotic liver disease.World journal of gastroenterology · 2024Article
- Relationship of the Degree of Sarcopenia with the Severity of Nonalcoholic Fatty Liver Disease and Cardiometabolic Risk in Adolescents.Life (Basel, Switzerland) · 2024Article
- Comparing body composition measures in children with end stage liver disease using noninvasive bioimpedance analysis.BMC pediatrics · 2024Observational
- Osteosarcopenia in NAFLD/MAFLD: An Underappreciated Clinical Problem in Chronic Liver Disease.International journal of molecular sciences · 2023Review
- Preoperative myopenia and myosteatosis and their impact on postoperative complications in children with inflammatory bowel disease.Surgery today · 2023Article
- Relationship between obesity related indicators and non-alcoholic fatty liver disease in children: a systematic review and meta-analysis.Translational pediatrics · 2023Article
- Association between Regional Body Muscle Mass and Non-Alcoholic Fatty Liver Disease: An Observational Study Using Data from the REACTION Study.Journal of personalized medicine · 2023Article
- Fatty liver disease in children (MAFLD/PeFLD Type 2): unique classification considerations and challenges.Therapeutic advances in endocrinology and metabolism · 2023Review
- Primary Broiler Hepatocytes for Establishment of a Steatosis Model.Veterinary sciences · 2022Article
- Gender differences in the association of body composition and biopsy-proved nonalcoholic steatohepatitis.Hepatology international · 2022Article
- Lower skeletal muscle mass on CT body composition analysis is associated with adverse clinical course and outcome in children with COVID-19.La Radiologia medica · 2022Article
- Impact of Sarcopenia and Myosteatosis in Non-Cirrhotic Stages of Liver Diseases: Similarities and Differences across Aetiologies and Possible Therapeutic Strategies.Biomedicines · 2022Review
- Perspectives on Sarcopenia as a Predictor for Outcomes in Pediatric Patients with Chronic Liver Disease.Hepatic medicine : evidence and research · 2022Review
- The Association of Sarcopenia and Visceral Obesity with Lean Nonalcoholic Fatty Liver Disease in Chinese Patients with Type 2 Diabetes Mellitus.Journal of diabetes research · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, sarcopenia was identified as a risk factor for non-alcoholic fatty liver disease (NAFLD) in adults. We here investigated the association between skeletal muscle mass (SMM) and NAFLD in non-obese children and adolescents. A retrospective medical chart review was performed for individuals aged 9-15 years diagnosed with NAFLD. Healthy volunteers aged 9-15 years were recruited as controls. Participants were subject to laboratory tests, abdominal sonography, and multi-frequency bioelectrical impedance analysis. SMM data were calculated as the skeletal muscle-to-body fat ratio (MFR), and the diagnosis of fatty liver was established by abdominal sonography. The control and NAFLD groups included 73 and 53 individuals, respectively. No significant difference was observed in gender and body mass index (BMI) distribution between the groups. Mean MFR was significantly lower in individuals with NAFLD than in those without (0.83 vs. 1.04,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.