Evidence map›Paper›PMID 33086618›Full record

ArticleMetabolites2020

Relationships between Follicle-Stimulating Hormone and Adiponectin in Postmenopausal Women.

Wan-Yu Huang, Dar-Ren Chen, Chew-Teng Kor, Ting-Yu Chen, Po-Te Lin, Joseph Ta Chien Tseng, Hung-Ming Wu

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Role of Estrogen across Multiple Disease Mechanisms.Current issues in molecular biology · 2024
    Review
  5. Effect of Tamoxifen on Proteome Expression duringJournal of proteome research · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wan-Yu HuangPediatrics of Kung-Ten General Hospital, Taichung City 433, Taiwan.
Dar-Ren ChenComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-0897-4374
Chew-Teng KorInternal Medicine Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Ting-Yu ChenInflammation Research & Drug Development Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Po-Te LinInflammation Research & Drug Development Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Joseph Ta Chien TsengDepartment of Biotechnology and Bioindustry Sciences, National Cheng-Kung University, Tainan 701, Taiwan.ORCID 0000-0002-3304-6086
Hung-Ming WuInflammation Research & Drug Development Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Changhua Christian Hospital · TWChina Medical University · TWNational Cheng Kung University · TW

Funding

the Changhua Christian Hospital Research Foundation, Changhua City, Taiwan. 107-CCH-NPI-052, and 108-CCH-IRP-129the Ministry of Science and Technology,Taiwan MOST 106-2314-B-371-003
6 · The paper itself

Abstract

Beyond fertility, follicle-stimulating hormone (FSH) may exert action on adipocytes, which are the major source of adiponectin and leptin, linking to insulin resistance. Therefore, we evaluated the relationships between FSH and adipocyte-derived hormones. This cross-sectional study enrolled postmenopausal women aged 40-65 years. The variables measured in this study included clinical parameters, fasting levels of sex hormones, glucose, insulin, and adipokines. A total of 261 women without breast cancer, 88 women with breast cancer receiving tamoxifen, and 59 women with breast cancer receiving additional gonadotropin-releasing hormone analogs were enrolled in this study. Significant differences in the levels of adiponectin, leptin, and FSH were observed between the non-breast cancer group and the breast cancer groups. Spearman's rank test revealed significant associations of FSH with either body mass index (BMI) or homeostatic model assessment of insulin resistance (HOMA-IR) values in the non-breast cancer group. After adjusting for BMI, age, and menopause duration, FSH levels were significantly associated with adiponectin (

Indexed as

adiponectinand breast cancerFSHinsulin resistancepostmenopause

Identifiers

PMID33086618
PMCPMC7603381
OpenAlexW3093087956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.