Evidence map›Paper›PMID 33086613›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Chemometric Analysis of Extracts and Fractions from Green, Oxidized, and Microbial Fermented Teas and Their Correlation to Potential Antioxidant and Anticancer Effects.

Chan-Su Rha, Young Sung Jung, Jung-Dae Lee, Davin Jang, Mi-Seon Kim, Min-Seuk Lee, Yong Deok Hong, Dae-Ok Kim

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Osteoprotective Roles of Green Tea Catechins.Antioxidants (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chan-Su RhaAMOREPACIFIC R&D Center, Yongin 17074, Korea.
Young Sung JungDepartment of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID 0000-0001-5589-3721
Jung-Dae LeeOsulloc Tea R&D Center, Osulloc Farm Corporation, Seogwipo 63521, Korea.
Davin JangDepartment of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID 0000-0002-4532-7694
Mi-Seon KimDepartment of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea.
Min-Seuk LeeOsulloc Tea R&D Center, Osulloc Farm Corporation, Seogwipo 63521, Korea.
Yong Deok HongAMOREPACIFIC R&D Center, Yongin 17074, Korea.
Dae-Ok KimDepartment of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea.ORCID 0000-0001-9262-1354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous reports on phytochemicals in green tea (GT) and processed teas mainly focused on more representative compounds such as catechins. Here, we focus on the insignificantly studied non-catechin components in tea extracts, and explore the multivariate correlation between diverse phenolic compounds in tea and the in vitro antioxidant and anticancer effects. Extracts from GT and four types of processed teas were further divided into hydrophilic and hydrophobic fractions, whose phenolic compositions and antioxidant capacities were quantified using HPLC-MS and three antioxidant assays, respectively. For three types of teas, the anticancer effects of their extracts and fractions were assessed using cancer cell lines. The hydrophobic fractions had lower antioxidant capacities than the corresponding hydrophilic fractions, but exhibited superior antiproliferative effects on cancer cells compared with the whole extract and the hydrophilic fraction. Partial least squares-discriminant analysis revealed a strong correlation between the anticancer effects and the theaflavins and flavonols. Therefore, in addition to catechins, the hydrophobic fraction of tea extracts may have beneficial health effects.

Indexed as

anticancer effectantioxidant capacityfermented green teahigh-performance liquid chromatography-mass spectrometrymultivariate analysisoxidized green teapartial least squares-discriminant analysis

Identifiers

PMID33086613
PMCPMC7650543

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.