Evidence map›Paper›PMID 33086489›Full record

ArticleInternational journal of molecular sciences2020

Rapid Expansion of Virus-Specific CD4

Hyun Seok Kang, Wanqiu Hou, Byung S Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. The Safety ofViruses · 2026
    Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hyun Seok KangDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Wanqiu HouDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Byung S KimDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Northwestern University · US

Funding

National Multiple Sclerosis Society RG 4001-A6NIH HHS RO1 NS28752 and RO1 NS33008
6 · The paper itself

Abstract

The infection of susceptible mice with Theiler's murine encephalomyelitis virus (TMEV) induces a T cell-mediated demyelinating disease. This system has been studied as a relevant infection model for multiple sclerosis (MS). Therefore, defining the type of T cell responses and their functions is critically important for understanding the relevant pathogenic mechanisms. In this study, we adoptively transferred naive VP2-specific TCR-Tg CD4

Indexed as

Adoptive TransferAnimalsCardiovirus InfectionsCD4-Positive T-LymphocytesCell ProliferationCentral Nervous SystemCytokinesDemyelinating DiseasesForkhead Transcription FactorsInterferon-gammaInterleukin-17Mice, TransgenicReceptors, Antigen, T-CellSpecies SpecificityTheilovirusCytokinesForkhead Transcription FactorsFoxp3 protein, mouseInterferon-gammaInterleukin-17Receptors, Antigen, T-CelldemyelinationFoxP3+CD4+ T cellsinflammationTh cellsvirus

Identifiers

PMID33086489
PMCPMC7588906
OpenAlexW3092835696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.