ArticleJournal of cardiovascular imaging2020
An Analysis of Myocardial Efficiency in Patients with Severe Asymptomatic Mitral Regurgitation.
Article in Journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Contemporary diagnosis and treatment of valvular heart disease in Korea: a nationwide hospital-based registry study.Journal of cardiovascular imaging · 2024Article
- Mechanisms of left ventricular systolic dysfunction in light chain amyloidosis: a multiparametric cardiac MRI study.Frontiers in cardiovascular medicine · 2024Article
- Myocardial Fatigue: a Mechano-energetic Concept in Heart Failure.Current cardiology reports · 2022Review
- Myocardial Efficiency: A Reliable Load-independent Parameter of Cardiac Performance?Journal of cardiovascular imaging · 2020Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is difficult to determine left ventricular systolic performance in patients with severe mitral regurgitation (MR) since left ventricular ejection fraction (EF) could be preserved until the end stages of the disease. Myocardial efficiency (MEf) describes the amount of external work (EW) done by the left ventricle per unit of oxygen consumed (mVO₂). In the present study, we aimed to investigate MEf in patients with asymptomatic severe MR using a novel echocardiographic method.
methodsA total of 27 patients with severe asymptomatic MR and 26 healthy volunteers were included in this cross-sectional study. EW was measured using stroke volume and blood pressure, while mVO₂ was estimated using double product and left ventricular mass.
resultsThere were no differences between the groups with regards to EF (66% ± 5% vs. 69% ± 7%), while MEf was significantly reduced in patients with severe MR (25% ± 11% vs. 44% ± 12%, p < 0.001). This difference was maintained even after adjustment for age, gender and body surface area (adjusted
conclusionsMEf was significantly lower in patients with asymptomatic severe MR and preserved EF.
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