Evidence map›Paper›PMID 33085756›Full record

Trial reportBlood advances2020

Multicenter phase 2 study of daratumumab monotherapy in patients with previously treated Waldenström macroglobulinemia.

Jorge J Castillo, Edward N Libby, Stephen M Ansell, M Lia Palomba, Kirsten Meid, Catherine A Flynn, Carly Leventoff, Christopher B Hergott, Tomasz Sewastianik, Elizabeth A Morgan and 5 more

Open access · greenAbstract readClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Blood advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. CD38 as theranostic target in oncology.Journal of translational medicine · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. How to Sequence Therapies in Waldenström Macroglobulinemia.Current treatment options in oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Jorge J CastilloBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Edward N LibbyDivision of Medical Oncology, University of Washington, Seattle, WA.
Stephen M AnsellDivision of Hematology and Oncology, Mayo Clinic, Rochester, MN.
M Lia PalombaLymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Kirsten MeidBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Catherine A FlynnBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Carly LeventoffBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Christopher B HergottDepartment of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA; and.
Tomasz SewastianikDepartment of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA; and.
Elizabeth A MorganDepartment of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA; and.
Ruben CarrascoDepartment of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA; and.
Jonathan R FrommUW Hematopathology Laboratory, Department of Laboratory Medicine, University of Washington, Seattle, WA.
Guang YangBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Zachary HunterBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Steven P TreonBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA.
Dana-Farber Cancer Institute · USHarvard University · USMayo Clinic in Arizona · USMemorial Sloan Kettering Cancer Center · USUniversity of Washington Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Waldenstrom MacroglobulinemiaAntibodies, MonoclonalHumansReceptors, CXCR4Antibodies, MonoclonaldaratumumabReceptors, CXCR4

Identifiers

PMID33085756
PMCPMC7594378
OpenAlexW3094173553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.