Evidence map›Paper›PMID 33085753›Full record

SynthesisHealth policy and planning2021

Participatory learning and action cycles with women's groups to prevent neonatal death in low-resource settings: A multi-country comparison of cost-effectiveness and affordability.

Anni-Maria Pulkki-Brännström, Hassan Haghparast-Bidgoli, Neha Batura, Tim Colbourn, Kishwar Azad, Florida Banda, Lumbani Banda, Josephine Borghi, Edward Fottrell, Sungwook Kim and 8 more

Erratum issuedAbstract readMeta-Analysis
In one paragraph

Synthesis in Health policy and planning, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Anni-Maria Pulkki-BrännströmDepartment of Epidemiology and Global Health, Umeå University, Umeå S-901 87, Sweden.
Hassan Haghparast-BidgoliUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Neha BaturaUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Tim ColbournUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Kishwar AzadPerinatal Care Project, Diabetic Association of Bangladesh, 122 Kazi Nazrul Islam Avenue, Dhaka 1000, Bangladesh.
Florida BandaMaiMwana Project, Mchinji, Malawi.
Lumbani BandaParent and Child Health Initiative (PACHI), Area 14 Plot 171, Lilongwe, Malawi.
Josephine BorghiDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London, WC1H 9SH, UK.
Edward FottrellUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Sungwook KimWarwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.
Charles MakwendaParent and Child Health Initiative (PACHI), Area 14 Plot 171, Lilongwe, Malawi.
Amit Kumar OjhaEkjut, Plot no. - 556B, Potka Chakradharpur, West Singhbhum, Pin - 833102, Jharkhand, India.
Audrey ProstUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Mikey RosatoWomen and Children First (UK), United House, North Road, London, N7 9DP, UK.
Sanjit Kumer ShahaPerinatal Care Project, Diabetic Association of Bangladesh, 122 Kazi Nazrul Islam Avenue, Dhaka 1000, Bangladesh.
Rajesh SinhaEkjut, Plot no. - 556B, Potka Chakradharpur, West Singhbhum, Pin - 833102, Jharkhand, India.
Anthony CostelloUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.
Jolene SkordisUCL Institute for Global Health, UCL (University College London), 30 Guilford Street, London, WC1N 1EH, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

WHO recommends participatory learning and action cycles with women's groups as a cost-effective strategy to reduce neonatal deaths. Coverage is a determinant of intervention effectiveness, but little is known about why cost-effectiveness estimates vary significantly. This article reanalyses primary cost data from six trials in India, Nepal, Bangladesh and Malawi to describe resource use, explore reasons for differences in costs and cost-effectiveness ratios, and model the cost of scale-up. Primary cost data were collated, and costing methods harmonized. Effectiveness was extracted from a meta-analysis and converted to neonatal life-years saved. Cost-effectiveness ratios were calculated from the provider perspective compared with current practice. Associations between unit costs and cost-effectiveness ratios with coverage, scale and intensity were explored. Scale-up costs and outcomes were modelled using local unit costs and the meta-analysis effect estimate for neonatal mortality. Results were expressed in 2016 international dollars. The average cost was $203 (range: $61-$537) per live birth. Start-up costs were large, and spending on staff was the main cost component. The cost per neonatal life-year saved ranged from $135 to $1627. The intervention was highly cost-effective when using income-based thresholds. Variation in cost-effectiveness across trials was strongly correlated with costs. Removing discounting of costs and life-years substantially reduced all cost-effectiveness ratios. The cost of rolling out the intervention to rural populations ranges from 1.2% to 6.3% of government health expenditure in the four countries. Our analyses demonstrate the challenges faced by economic evaluations of community-based interventions evaluated using a cluster randomized controlled trial design. Our results confirm that women's groups are a cost-effective and potentially affordable strategy for improving birth outcomes among rural populations.

Indexed as

Perinatal DeathWomenBangladeshCost-Benefit AnalysisFemaleHumansIndiaInfant, NewbornMalawiNepalRandomized Controlled Trials as Topiccommunity mobilizationcost-effectiveness analysisCostsmaternal and child healthrandomized controlled trial

Identifiers

PMID33085753
PMCPMC7886438

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.