ArticlePloS one2020
Association between the retinal vascular network and retinal nerve fiber layer in the elderly: The Montrachet study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Plasma Vitamin D and Intermediate Age-Related Macular Degeneration: Insights from the Longitudinal ALIENOR Study.Ophthalmology science · 2026Article
- Retinal vessel tortuosity and fractal dimension in diabetic retinopathy.International journal of retina and vitreous · 2025Article
- Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are?Translational vision science & technology · 2025Article
- Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?Journal of clinical medicine · 2022Review
- An Evaluation of Choroidal and Retinal Nerve Fiber Layer Thicknesses Using SD-OCT in Children with Childhood IgA Vasculitis.Diagnostics (Basel, Switzerland) · 2022Article
- Comparison of peripapillary retinal nerve fiber layer and macular thickness in non-diabetic chronic kidney disease and controls.PloS one · 2022Article
- Increased retinal venular calibre in acute infections.Scientific reports · 2021Article
- A narrative review of retinal vascular parameters and the applications (Part I): Measuring methods.Brain circulationReview
- Retinal Biomarkers for Alzheimer Disease: The Facts and the Future.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the association between the characteristics of the retinal vascular network in the elderly and retinal nerve fiber layer (RNFL) thickness in a population-based study.
methodsWe conducted a population-based study, the Montrachet study (Maculopathy Optic Nerve, nuTRition neurovAsCular, and HEarT disease), in participants aged ≥ 75 years. RNFL thickness was assessed with spectral-domain optical coherence tomography (SD-OCT). Analysis of the retinal vascular network was performed by means of the Singapore "I" Vessel Assessment (SIVA) software based on fundus photography.
resultsData from 970 participants were suitable for analysis. Patients with optic neuropathy were excluded. In multivariable analysis, each standard deviation (SD) decrease in the caliber of the six largest arterioles and veins in zone B and the six largest arterioles and veins in zone C was associated with a decrease in global RNFL thickness (β = -1.62 μm, P = 0.001; β = -2.39 μm, P < 0.001; β = -1.56 μm, P = 0.002; and β = -2.64 μm, P < 0.001, respectively).
conclusionsOur study found that decreased retinal vessels caliber were associated with a decreased RNFL thickness in the elderly without optic neuropathy.
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