Evidence map›Paper›PMID 33085116›Full record

Trial reportSociology of health & illness2021

Universal HIV testing and treatment and HIV stigma reduction: a comparative thematic analysis of qualitative data from the HPTN 071 (PopART) trial in South Africa and Zambia.

Lario Viljoen, Virginia A Bond, Lindsey J Reynolds, Constance Mubekapi-Musadaidzwa, Dzunisani Baloyi, Rhoda Ndubani, Anne Stangl, Janet Seeley, Triantafyllos Pliakas, Peter Bock and 6 more

Abstract readClinical Trial
In one paragraph

Trial report in Sociology of health & illness, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lario ViljoenDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Desmond Tutu TB Centre, Stellenbosch University, Stellenbosch, South Africa.ORCID 0000-0003-4039-6639
Virginia A BondZambart, School of Public Health, Ridgeway Campus, University of Zambia, Lusaka, Zambia.ORCID 0000-0002-6815-4239
Lindsey J ReynoldsDepartment of Sociology and Social Anthropology, Stellenbosch University, Stellenbosch, South Africa.
Constance Mubekapi-MusadaidzwaDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Desmond Tutu TB Centre, Stellenbosch University, Stellenbosch, South Africa.ORCID 0000-0003-4430-7461
Dzunisani BaloyiDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Desmond Tutu TB Centre, Stellenbosch University, Stellenbosch, South Africa.ORCID 0000-0003-3315-0411
Rhoda NdubaniZambart, School of Public Health, Ridgeway Campus, University of Zambia, Lusaka, Zambia.
Anne StanglInternational Center for Research on Women, Washington, DC, USA.ORCID 0000-0001-9325-5077
Janet SeeleyGlobal Health and Development Department, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-0583-5272
Triantafyllos PliakasDepartment of Public Health, Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-7242-6479
Peter BockDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Desmond Tutu TB Centre, Stellenbosch University, Stellenbosch, South Africa.ORCID 0000-0003-3211-6078
Sarah FidlerImperial College NIHR BRC, Imperial College London, London, UK.ORCID 0000-0003-1676-7583
Richard HayesDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-1729-9892
Helen AylesZambart, School of Public Health, Ridgeway Campus, University of Zambia, Lusaka, Zambia.ORCID 0000-0003-4108-2842
James R HargreavesDepartment of Public Health, Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-3509-3572
Graeme HoddinottDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Desmond Tutu TB Centre, Stellenbosch University, Stellenbosch, South Africa.ORCID 0000-0001-5915-8126
HPTN 071 (PopART) study team

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
HIV Prevention trials Network (HPTN) Coordinating and Operations CenterU01AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI VERMUND, STEN H. · 2006 to 2010
$72.7M
Leadership for HIV/AIDS Clinical Trials Networks; HIV Prevention Trials NetworkU01AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DONNELL, DEBORAH J · 2006 to 2010
$28.8M
HIV Prevention Trials Network: Network LaboratoryU01AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ESHLEMAN, SUSAN H · 2006 to 2010
$16.5M
Medical Research Council MR/K012126/1Medical Research Council MR/R010161/1NIAID NIH HHS U01 AI068613NIAID NIH HHS U01 AI068617NIAID NIH HHS U01 AI068619NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619
6 · The paper itself

Abstract

Despite continued development of effective HIV treatment, expanded access to care and advances in prevention modalities, HIV-related stigma persists. We examine how, in the context of a universal HIV-testing and treatment trial in South Africa and Zambia, increased availability of HIV services influenced conceptualisations of HIV. Using qualitative data, we explore people's stigma-related experiences of living in 'intervention' and 'control' study communities. We conducted exploratory data analysis from a qualitative cohort of 150 households in 13 study communities, collected between 2016 and 2018. We found that increased availability of HIV-testing services influenced conceptualisations of HIV as normative (non-exceptional) and the visibility of people living with HIV (PLHIV) in household and community spaces impacted opportunities for stigma. There was a shift in community narratives towards individual responsibility to take up (assumingly) widely available service - for PLHIV to take care of their own health and to prevent onward transmission. Based on empirical data, we show that, despite a growing acceptance of HIV-related testing services, anticipated stigma persists through the mechanism of shifting responsibilisation. To mitigate the responsibilisation of PLHIV, heath implementers need to adapt anti-stigma messaging and especially focus on anticipated stigma.

Indexed as

HIV InfectionsHIV TestingHumansSocial StigmaSouth AfricaZambianormalisationresponsibilisationstigmasub-Saharan Africauniversal test and treat

Identifiers

PMID33085116
PMCPMC7894283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.